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Operator
Ladies and gentlemen, thank you for standing by.
Welcome to the QuintilesIMS Second Quarter 2017 Earnings Conference Call.
(Operator Instructions) As a reminder, this conference is being recorded, Thursday, August 3, 2017.
I would now like to turn the conference over to Andrew Markwick, Vice President, Investor Relations.
Please go ahead.
Andrew Markwick - VP, IR
Thank you, Alec.
Good morning, everyone.
Thank you for joining our second quarter 2017 earnings call.
With me today are Ari Bousbib, Chairman and Chief Executive Officer; and Michael McDonnell, Executive Vice President and Chief Financial Officer.
Today, we'll be referencing a presentation that will be visible during this call for those of you on our webcast.
This presentation will be available following the call on the Events & Presentations section of our QuintilesIMS Investor Relations website at ir.quintilesims.com.
Before we begin, I would like to caution listeners that certain information discussed by management during this conference call could include forward-looking statements.
Actual results could differ materially from those stated or implied by forward-looking statements due to risks and uncertainties associated with the company's business, which are discussed in the company's filings with the Securities and Exchange Commission, including our annual report on Form 10-K filed on February 16, 2017, and subsequent SEC filings.
In addition, we will discuss certain non-GAAP financial measures on this call, which should be considered a supplement to, and not a substitute for, financial measures prepared in accordance with GAAP.
A reconciliation of these non-GAAP measures to the comparable GAAP measures is included in the press release and conference call presentation.
I would also like to point out that as with other global businesses, we have been impacted by year-over-year foreign exchange fluctuations.
I would now like to turn the call over to our Chairman and CEO, Ari Bousbib.
Ari Bousbib - Chairman, CEO and President
Thank you, Andrew, and good morning, everyone.
Thank you for joining our second quarter 2017 earnings call.
Q2 was another solid quarter for the QuintilesIMS team.
Strong operational discipline and execution of our integration plans are driving results.
Let's review the quarter.
Consistent with the last couple of quarters, we're making comparisons more meaningful by discussing results on a combined company basis as if the merger took place January 1, 2016.
Second quarter revenue was at the high end of our guidance range of $1.97 billion.
This revenue included $871 million for Commercial Solutions, $896 million for R&D Solutions and $204 million for Integrated Engagement Services.
Adjusted EBITDA for the company was also close to the high end of our guidance range at $486 million.
As a result, our adjusted EBITDA margins expanded 100 basis points for the quarter.
Let me provide some color behind the numbers.
Let's start with our technology solutions business.
Our tech business continues to gain traction in the market.
Let me illustrate with a few examples.
During the quarter, we signed 2 significant deals with top 10 pharma clients for our social media technology platform for over $12 million.
As a reminder, our social media technology mines and analyzes over 400,000 social media outlets to track patient sentiment.
It specifically flags adverse events to help clients rapidly identify or remediate issues when they arise and satisfy regulatory reporting requirements.
We do this through proprietary ontology in 52 languages, proprietary algorithms, 24/7, 365 days of the year in a state-of-the-art global monitoring center.
We also had significant wins with our master data management or MDM platform amounting to about $20 million with top 20 pharma clients.
The clients will deploy our MDM solution globally, benefiting from QuintilesIMS's global implementation services, which are unmatched by our competitors.
Finally, in another illustration of progress in our technology business, we issued a press release on June 26 highlighting the launch of our new Orchestrated Customer Engagement, or OCE, SaaS offering.
The OCE offering will be released towards the end of the year.
We are in fact accelerating investments in our salesforce.com partnership to replatform our global CRM and MCM solutions.
Stay tuned for new product releases, including in the clinical space.
Switching to our Real-World Insights business, where we also landed a few significant wins during the quarter.
First, a $15 million Real-World project with a top 10 pharma client.
This particular win in cardiovascular leverage a direct-to-patient, data-driven approach that enables us to shorten time lines and accelerate patient recruitment for the project.
The second multi-million dollar win I want to highlight in our Real-World business is with a top biotech company, where we displaced the existing preferred provider for a first-in-class, new-to-market product.
Here, we applied a differentiated approach by linking primary site and investigator data from legacy Quintiles with existing secondary claims data from legacy IMS, a capability that is unmatched by our competitors.
Moving to our R&D business.
We saw continued improvements and another quarterly sequential increase in our as-contracted bookings.
At the end of the quarter, we had a contracted backlog of just under $10 billion.
To be precise, $9,990,000,000.
Now I know there is a lot of discussion about market trends in the R&D space and in the CRO space, so let me tell you what we see in the market.
On a macro level, the total number of molecules in clinical development continues to increase across all stages of the pipeline.
The number of molecules in Phase I, II and III are at the highest levels since at least 2001.
FDA approvals in 2017 are tracking well ahead of 2016.
As you all know, FDA Commissioner Gottlieb has signaled policy and regulatory shifts that we believe will support life sciences innovation, potentially accelerating clinical development and reducing regulatory risk.
On a micro level at QuintilesIMS and in addition to these underlying market forces, integration efforts are enabling us to rethink how operations are conducted, and we are laser-focused on modernizing the approach we take to many of the traditional CRO processes.
We are in fact winning business with clients that the legacy Quintiles organization had done very little R&D work with in the past.
And we have specifically secured wins with previously locked-out accounts.
Now you are familiar with our next-gen clinical development offering.
It's been instrumental in supporting these wins.
In fact, more than $600 million of awards since the merger have leveraged next-gen capabilities.
We are also winning with emerging biopharma clients, and I'd like to give a couple examples of next-gen EBP wins that, in combination, have a value of $50 million.
The first example is a win in Asia, where the client selected us because of our ability to provide an end-to-end solution, from evidence driven protocol design to precision site ID.
The second example is a sole provider win in Europe, which was driven by our ability to leverage our real-world data, advanced analytics and domain expertise, in combination to answer the client's strategic therapeutic questions in COPD and asthma.
I also want to provide a quick update on progress with the $120 million fixed-price award that we won with a top 5 pharma client last quarter and which we discussed on the call.
To date, we greatly exceeded all of the legacy Quintiles historical time line benchmarks across all geographies.
In fact, the client awarded us 2 additional multimillion dollar full service contracts in other therapeutic areas during the quarter, demonstrating their confidence in our solutions.
As a reminder, legacy Quintiles had done virtually no full-service clinical work with these clients over the previous 6-year period.
Now the traction we see in the marketplace for our next-gen solution has led us to accelerate investments in next-gen operationalization and resourcing plans.
Once again, we see that in each of our business, the basis for our differentiation continues to be our integrated approach to rich data, new technologies, advanced analytics and significant domain expertise.
Of course, we are striving to be best-in-class in each of these capabilities.
But what truly sets us apart is the way we integrate these capabilities across the portfolio to bring highly differentiated solutions within each of the clinical and commercial markets we operate in.
Before I turn it over to Mike, I would like to announce that we are holding an analyst and investor conference in New York City later this year.
Please hold the date of November 8. We're planning a morning event, probably running from 8:00 a.m.
to 1:00 p.m..
And this will be shortly after our third quarter earnings call, the focus will not be on the numbers, but on the launch of strategy and progress of the business.
The day will highlight some of our technology capabilities and will be more comprehensive than the demos some of you have already seen.
More importantly, this will give you all an opportunity to meet a broader cross-section of management.
We're looking forward to this event and hope you can all attend.
With that, let me turn it over to Mike McDonnell, our Chief Financial Officer, to take you through the financials in more detail.
Michael R. McDonnell - CFO and EVP
Thank you, Ari, and good morning, everyone.
Q2 was another solid quarter for QuintilesIMS.
Let's review the details.
As in previous quarters, I would like to call your attention to the more meaningful combined company comparisons in the center of the page.
Second quarter revenue was $1.97 billion, which was the high end of the guidance range we provided last quarter.
You will recall the deferred revenue adjustment we highlighted on the last couple of calls.
This quarter, it negatively impacted revenue by $2 million.
When adjusting for this and on a combined company basis, second quarter revenue grew 1.2% at constant currency and 0.1% reported.
On a combined company basis, Commercial Solutions revenue of $871 million grew just under 2% at constant currency and 0.6% reported.
The Commercial Solutions growth rate was again impacted by a decline in the legacy Quintiles Encore business and headwinds from the legacy Quintiles advisory consulting business.
Excluding Encore, growth in Commercial Solutions was about 2.5% at constant currency.
We sold the Encore business after the close of the second quarter and recorded an impairment charge in Q2 to reflect the sales price.
This business is not part of our strategic vision.
And as a result of the sale, we will have some tax benefits.
R&D Solutions service revenue of $896 million grew 1.7% at constant currency and 0.4% at actual FX rates.
Growth was impacted by a decline in our early clinical development business due to the closing of a facility in Europe during 2016 as well as weaker bookings and higher cancellations in the third quarter of 2016.
When adjusting for the early clinical development business, R&D growth at constant currency was about 3%.
Integrated Engagement Services revenue of $204 million declined 2.1% at constant currency and 3.7% at actual FX rates.
Revenue growth in the IES segment was impacted by a onetime $9 million royalty acceleration in 2016.
Turning now to profit.
Second quarter adjusted EBITDA was $486 million and our adjusted EBITDA margin of 24.7% expanded 100 basis points.
GAAP net income was $75 million and GAAP diluted earnings per share was $0.34.
Adjusted net income was $242 million and adjusted diluted earnings per share was $1.09 in the quarter.
Now let's turn to the results for the first half.
Again, I would like to call your attention to the more meaningful combined company comparisons in the center of the page.
First half revenue was just under $3.9 billion.
Adjusting for deferred revenue and on a combined company basis, first half revenue grew 2.2% at constant currency and 1% reported.
On a combined company basis, Commercial Solutions revenue of $1.72 billion grew 2.1% at constant currency and 0.9% reported.
Excluding Encore, Commercial Solutions growth was about 3% at constant currency.
R&D Solutions service revenue of $1.76 billion grew 2.9% at constant currency and 1.7% at actual FX rates.
Excluding the early clinical development business, revenue growth was 4% at constant currency.
Integrated Engagement Services revenue of $400 million declined 1.2% at constant FX and 2.3% reported.
Turning to R&D Solutions' net new business and backlog.
For the 12 months ended June 30, 2017, R&D Solutions' as-contracted bookings were $4.03 billion, resulting in an ending contracted backlog of $9.99 billion.
We expect to convert approximately $3 billion of this backlog into revenue over the next 12 months.
As you know, we began reporting our bookings on an as-contracted basis rather than an as-awarded basis.
This approach began with the third quarter of 2016, which was the last quarter of Quintiles' standalone reporting.
As we now have 4 quarters on the as-contracted approach, we feel that it is appropriate to provide some additional color on the bookings.
As you can see from the chart, our bookings trend has improved steadily each quarter since we closed the merger.
For the last 12 months since we started reporting as contracted, the book-to-bill is 1.14.
Looking at the last 9 months since we closed the merger and began reporting on a combined basis, the book-to-bill is 1.21.
Looking at the last 6 months since the beginning of 2017, the year-to-date book-to-bill is 1.24.
And looking at this quarter, we had a book-to-bill of 1.30.
Now, if you were to back calculate the book-to-bill in the quarter by taking the difference in backlog and backing out revenue, you would get a book-to-bill on the quarter of 1.37.
This includes a small positive benefit from the revaluation of the entire ending backlog at spot FX rates at the end of the quarter.
We feel that using for bookings the same average rate used for revenue over the quarter is a better indication of actual activity in the quarter, allows for more consistent comparisons across periods, and in this case, is more conservative.
Turning now to profit for the first half of the year.
First half adjusted EBITDA was $953 million and our adjusted EBITDA margin of 24.6% expanded 50 basis points.
GAAP net income was $149 million and GAAP diluted earnings per share was $0.65 for the first 6 months of 2017.
Adjusted net income was $480 million.
Adjusted diluted earnings per share was $2.10 in the first half of the year.
Let's spend a few minutes on the balance sheet.
At June 30, cash and cash equivalents totaled $902 million and debt was about $9 billion, resulting in net debt of about $8.1 billion.
Our gross leverage ratio was 4.5x trailing 12-month adjusted EBITDA.
Net of cash, our leverage ratio was 4.1x.
Cash flow from operating activities was $245 million in the second quarter.
Capital expenditures were $100 million and free cash flow was $145 million.
During the second quarter, the board approved an increase in our post-merger share repurchase authorization by an additional $1 billion to $3.5 billion.
We repurchased $300 million worth of our shares from our private equity sponsors and the legacy Quintiles founder at the end of May.
And towards the end of the quarter, we repurchased an additional $78 million worth of our shares in the open market for a total of $378 million of repurchases during the quarter.
At the end of the second quarter, we had $853 million remaining of our share repurchase authorization.
Let's now turn to guidance.
We are reaffirming our full year 2017 revenue and adjusted EBITDA guidance and raising our full year adjusted diluted EPS guidance by $0.05.
You will recall that we also increased the 2017 EPS guidance range by $0.05 last quarter.
Assuming currency rates remain at current levels for the rest of the year, we expect total revenue of $8 billion to $8.1 billion; adjusted EBITDA to be between $2 billion and $2.1 billion; and adjusted diluted EPS to be between $4.50 and $4.65, up from $4.45 to $4.60.
The basis for our adjusted diluted EPS raise is a change in our adjusted book tax rate expectation.
To date, our adjusted book tax rate has been approximately 29%, and we anticipate it will remain at this level for the rest of the year.
This incremental 1% benefit below the line will increase our adjusted diluted EPS by approximately $0.05 for the year.
For our cash tax rate, we now expect approximately 15% for the year, down from our previous guidance of approximately 16%.
For the third quarter of 2017, assuming today's FX rates remain constant through the end of the quarter, we expect revenue to be between $2 billion and $2.03 billion, reflecting the general strength of the business; adjusted EBITDA to be between $500 million and $515 million, reflecting continued operational improvements, offset by accelerated investments in next-gen capability development, as Ari mentioned, as well as accelerated investments in salesforce.com, CRM and MCM replatforming efforts in anticipation of the upcoming product launch later this year; and adjusted diluted EPS to be between $1.10 and $1.15.
In summary, we had another solid quarter.
We delivered on our financial commitments.
We are investing in all areas of the business for future growth.
We are making progress with the salesforce.com alliance and we remain excited about upcoming product releases for both clinical and commercial technology.
We have a strong R&D Solutions pipeline.
Next gen continues to gain traction with new wins in the quarter, and we continue to deploy our capital effectively and have bought back $2.7 billion worth of our shares at an average price of $78.81 since we closed the merger.
With that, I would like to ask Alex to please open the lines for Q&A.
Operator
(Operator Instructions) Our first question comes from the line of Tim Evans with the company Wells Fargo.
Timothy Cameron Evans - VP and Senior Equity Analyst
So just using your cash flow statement as a proxy, you've spent over $250 million on acquisitions in the first half of the year, which is a pretty sizable outlay.
Can you just talk about these a little bit?
What did you do?
What segments were they in?
How much did they contribute to growth in the first half?
And how much revenue are they expected to add for the full year?
Ari Bousbib - Chairman, CEO and President
Thanks for your question.
This is Ari.
In the quarter, I think we spent $180 million in acquisitions.
We continuously look for and have a rich pipeline of small tuck-in capability acquisitions.
These are, for the most part, and I want to say exclusively this year, technology acquisitions, both in the commercial space and in the clinical space.
This quarter, there were a few handful of small acquisitions, all of which closed at the end of the quarter and had 0 impact in the quarter.
As we've told you before, we may pay a healthy premium because again, we're buying technology capabilities.
It's a decision to continue to develop our assets through acquisitions instead of internal product development spend.
Initially, these acquisitions have very little revenue contribution and the acquisition spend can be lumpy quarter-to-quarter.
But that's what we've signaled before.
It's not rich.
And we expect, to answer your question in terms of contribution to revenue, that acquisitions will contribute year in, year out, 1 point, 1.5 points to our growth, and this year won't be different.
Timothy Cameron Evans - VP and Senior Equity Analyst
Okay, great.
And then the CapEx spending...
Ari Bousbib - Chairman, CEO and President
And by the way, this will be true both for R&D and commercial, just to be complete.
Go ahead.
Timothy Cameron Evans - VP and Senior Equity Analyst
Okay.
I was just going to say the CapEx in the quarter was up sequentially by a fairly meaningful amount.
Is that the run rate we should expect going forward kind of on your quarterly CapEx?
Michael R. McDonnell - CFO and EVP
So Tim, it's Mike speaking.
Overall, yes, it did tick up a little bit.
I would attribute that more to timing if you compare the first quarter to the second quarter.
And I would say that in general, we continue to see ourselves as a company that is not capital-intensive.
The combined company should run at about 4% of revenue in general.
And early on, it could be a little bit higher in the early years as we integrate the 2 businesses.
Year-to-date, we're at about 4.5%, and I think first quarter, second quarter is strictly timing.
Operator
Our next question comes from the line of Jack Meehan with the company Barclays.
Jack Meehan - VP and Senior Research Analyst
I wonder -- it looks like you've shown some good momentum in terms of the net new business awards.
I was wondering if you could talk a little bit about the recent cancellation activity, how things have gone since the end of the first quarter and anything notable there.
Ari Bousbib - Chairman, CEO and President
Well, I mean, every quarter we have cancellations.
Bear in mind, we moved to an as-contracted basis and that's the same for cancellations, right?
So that could be that there was a cancellation a quarter or 2 ago and we took it in this quarter.
So we had, as in every quarter, cancellations this quarter as well in terms of contracted.
Nothing of significance in terms of, in the quarter, new cancellations.
The cancellations we took and that are reflected in our numbers are cancellations that were announced in prior periods.
Nothing of significance this quarter.
You know we have a very dispersed client base and that there is, at the moment, not any given trial that will materially impact us.
Jack Meehan - VP and Senior Research Analyst
Great.
That's helpful commentary.
And then just one in terms of the progress in terms of the cost synergies.
It looked like you showed some good leverage there in the second quarter with the higher revenue.
Just if you have any additional thoughts on the pacing for getting to the $200 million over the next few years, that would be helpful.
Ari Bousbib - Chairman, CEO and President
Yes.
I mean, we've said that it's really starting to kick in, in '18 and there is around -- our goal is to get to our couple of hundred of million dollars of cost synergies, merger-related cost synergies, at the end of '19 in terms of a run rate.
So yes, that's the ramp.
I mean, in terms of -- normally, if we gave -- it's not linear, as you know, right?
I mean, we will have some benefit in '18 and then it will ramp in 2019 and we get to our $200 million run rate at the exiting 2019.
Is it going the way we anticipate?
In some areas, it's going faster.
And in some areas, as always, slower.
There are a lot of moving parts.
Some of the real estate consolidations in some countries are easy to do, others are more difficult.
Some of the IT systems, again in HR, it's going well.
On the financial side, we have some delays.
But again, nothing that's not -- that's unusual.
All in all, I think we see we have good visibility and we're tracking on our plans.
Operator
Our next question comes from the line of Eric Coldwell with the company Baird.
Eric White Coldwell - Senior Research Analyst
Don't take this as a critique at all, but technically, at least compared to those of us on the sell side, you did push out revenue and EBITDA expectations quarterly throughout the year, but you also maintained your revenue and EBITDA guidance for the year.
So it does put a lot more attention on the fourth quarter.
And with that lead in, my question is or maybe my ask is, help convince me and others that the fourth quarter is in fact going to be a strong quarter.
And how do you get to your guidance for the full year?
What are the inputs in the fourth quarter that really stand out for you both in terms of revenue and EBITDA?
And I might have one follow-up.
Ari Bousbib - Chairman, CEO and President
Okay, Eric.
I know you have a follow-up for sure.
So the -- look, the guidance we gave is based on our forecasts both for -- every time we did so for the quarter and for the year.
Our guidance on revenue and EBITDA has a range and has changed -- that has not changed.
As always, there are puts and takes; aspects of the business are doing better than we thought and others are perhaps weaker than we had anticipated.
We also, as you know, got rid of the Encore business earlier this month or last month.
And so it won't be in our numbers any longer, so that piece of the revenue is out.
Flip side is we have a little bit -- assuming the FX rates remains where they are, we may have a little bit of tailwind from FX, which will offset that loss of revenue.
And bear in mind, normally the FX rate is rather a headwind on EBITDA rather than a tailwind that it may be on revenue simply because we do a lot of work overseas.
And at the EPS line, we are hedged largely because we've got also euro-denominated currencies.
And the FX movements are very complicated because of the number of countries in which we do business and the large number of currencies that are fluctuating constantly.
So with respect to your specific questions in terms of the ramp, look, there are some merger-related costs that we've had throughout the first 2 quarters and we believe will continue in the third quarter.
I've said before, there are redundant costs that we continue to carry, that we cannot adjust out of the P&L, of our adjusted EBITDA numbers.
Those are going to continue in the third quarter, and a portion of those are going to be -- we're going to be able to remove in the fourth quarter.
So that's one aspect.
Secondly, there are -- when we planned for the year, we had anticipated a progression of our investments in both the R&D side and the technology side.
We are actually accelerating some of these investments and our resourcing plans.
And so the third quarter carries some of that.
In a sense, it -- some of the investments that had been planned in Q4 will take place in Q3.
That's another reason why you might see a bigger ramp than you might have otherwise anticipated.
We also announced the salesforce.com initiative alliance, which, again, we had not anticipated earlier in the year.
And that is causing us to invest more in people and software development and so on.
And again, all of that is also accelerating because we now believe we'd be able to launch the products towards the end of the year.
So all of that affects, if you will, the ramp on EBITDA in the fourth quarter, but nothing unusual.
Each of those is a relatively small number in isolation and it's the accumulation of that, that perhaps give that -- gives you the sense that it's a bigger ramp in the fourth quarter.
Eric White Coldwell - Senior Research Analyst
Ari, did I also understand, at one point, I think in a past conversation, you might have mentioned -- or perhaps it was Mike that mentioned, you might have had some contract timing issues in the fourth quarter.
I know you've talked about seasonality, but are there unusual initial contract timing events?
Ari Bousbib - Chairman, CEO and President
Yes.
Well, again, for those of you less familiar with the IMS, the IMS Commercial business traditionally -- Q4, traditionally, has a seasonality element to it.
It's the end of the year, and pharma has budgets that -- marketing and commercial budgets that they look to spend.
And the fourth quarter typically has been the strongest.
A lot of purchases of what we call ad hoc data packages, most of that comes at the end of the year.
So if you look historically, the IMS legacy business is weaker in the third quarter.
I think Q2, we had seasonality -- seasonality of Q3 has been the weakest historically and Q4 the strongest.
So that will explain also perhaps the perception of a bigger ramp in the fourth quarter.
Eric White Coldwell - Senior Research Analyst
My quick follow-up, if I'm allowed, is just -- I'm sorry if I missed it, but I'd love to get an update on your sales and marketing headcount and development of your teams in the field.
Maybe qualitative as well as quantitative commentary there would be helpful.
Ari Bousbib - Chairman, CEO and President
Okay.
Thank you for the question and thanks for bringing this up.
We have said before that -- and I'm assuming you're asking primarily on the R&D side, which is where we felt that we're -- we had Commercial -- perhaps it's been not as forceful and aggressive as we could have been historically.
Eric White Coldwell - Senior Research Analyst
That's right.
Ari Bousbib - Chairman, CEO and President
So I think we had around 150 salespeople historically in the R&D business.
And it's not easy to ramp up to where we want to be, but we have increased that number materially by probably about 50% at this point.
And secondly, we have also trained -- as you know, we've said before, we've reorganized our go-to-market strategy globally and we have regionalized the go-to market approaches in North America, Europe and Asia.
And we have combined our accounts managements across clinical and commercial markets.
We have, in the process, trained 1,000 legacy IMS salespeople on R&D business development.
So they are helping us opening doors, create the meetings that otherwise would simply not have been open to the legacy Quintiles organization before.
We -- they are able to engage in conversations, learn about RFPs earlier in the process and involve then the domain experts from the R&D organization at the right time.
So again, in terms of numbers specifically, we continue to ramp up the salesforce recruitment dedicated to R&D.
We've increased that salesforce that's dedicated and specialized by about 50% to date.
And we have also trained 1,000 IMS salespeople in I feel the earlier stages of business development and sales for R&D as well.
Thanks for your question.
Operator
(Operator Instructions) Our next question comes from the line of John Kreger with the company William Blair.
John Charles Kreger - Partner and Healthcare Services Analyst
Ari, I think in the past, you've talked about fully automating E360 by around year-end.
Could you just give us an update on where that process stands?
Ari Bousbib - Chairman, CEO and President
Yes.
Thank you for the question, John.
Look, when we say -- what we really wanted to do -- there's always an element of customization, right?
Every study is unique.
What we wanted to do, and we said this upfront, is to try to "productionize" the process, to accelerate our response time and minimize the degree of customization.
Again, there will always be an element of customization.
We are well on our way, by the end of the year to having "productionized," which means having loaded the data and standardized the data mining and algorithms required to accelerate site identification, optimal site identification for a given product or design for a dozen main therapies.
The issue is how fast can you go across all specific decision therapies.
So we think that this is going to cover probably 80% to 90% of the RFPs in which we believe next gen will be relevant and useful, which, as we said before, is at least half of the portfolio or the pipeline.
So that's where we are today and this is exactly where we wanted to be.
The biggest hurdle is to recruit the type of people that we need.
Today, we have 110, I think, by the last time I saw, of people in what we call the AOCE -- the advanced Analytics Center of Excellence.
And that's the full-time dedicated team -- the ACOE, I'm sorry, I don't remember what it stands for, but advanced Analytics Center of Excellence, in which we have created, reporting to Cynthia Verst and led by Natalia Balko, who some of you have met.
We have this team of over 100 people full-time working on the operationalization of how we respond to RFPs, where we think next gen has relevance.
Bear in mind, we are also trying to use next gen in the existing set of trials that we are working on and it's really the same team.
So at this time, the main constraint to even going faster than we have thought is simply the ability to recruit to the type of people we want.
I mean, we're really having data scientists, statisticians, software development.
People is just not so easy to recruit globally, but we're making good progress.
John Charles Kreger - Partner and Healthcare Services Analyst
And then a follow-up.
I think you'd suggested that this data would help you have more confidence in RFPs and bidding and therefore, experimenting with fixed price awards.
It sounds like that first big one's going very well.
Are you rolling that strategy out more broadly in awards that you've had in the last 3 months?
Ari Bousbib - Chairman, CEO and President
Yes, we are.
Again, we will speak some more about this at our November Investor Day.
We aim for nothing short of disrupting the way clinical trials are conducted.
Historically, this is an industry that's paid for inefficiency.
And it is one -- the biggest problem in health care is inefficiency over inefficiency.
People are paid for time.
And without knocking on any specific profession is -- the longer it takes -- it's like lawyers.
The longer it takes, the more time you take and the more money you make.
The more costs you have because essentially your cost plus type of business model, from an economic standpoint, the more cost you have, the more waste you have, the more rework you have, the more change orders you have, the more revenue you generate.
And so there is a kind of an inherent conflict in the industry where no one wants to shoot themselves in the foot, so to speak, and damage their business model.
Well, we want to change that.
We believe that with more visibility, more predictability, more data-enabled and technology-enabled processes, you can actually share risk with clients in a better way with more visibility, an educated risk, and we are willing to do it.
And our early forays into this business model change show that clients are A, much more receptive; and B, see the results in trials that are very complex, like the one I discussed before.
Now again, this is not just a hurdle to overcome because the whole industry is based on a different type of business model.
Clients are accustomed doing business differently, and even our own people are accustomed to doing business differently.
So it's sort of a cultural overhaul that we need, and we believe strongly in this vision and we want to move forward.
It's too early to show you metrics because we don't have enough of those.
And as you know, it's a long-cycle business.
So even if we win a trial today, it's going to take time.
Now, this particular trial is very large, very complex.
It's with a previously essentially locked-out account.
There are many people competing in the same therapy.
It's an oncology therapy, and so site identification is even more difficult and we're beating all time lines historically, and we're specifically tracking.
Now one trial is not enough to make it a science, but we feel very confident.
And hopefully, over time, we developed enough of a database to support the thesis.
And I can tell you, clients are extremely receptive to our vision.
Operator
Our next question comes from the line of Sandy Draper with the company SunTrust.
Alexander Yearley Draper - MD
A question, Ari, in terms on the IMS technology side.
Just trying to think about the product road map.
I remember, I don't know, 1.5 years, maybe 2 years ago, you guys were talking about, after the Cegedim acquisition, the new Internet platform.
And you had gotten a little traction with some smaller biotechs, I think on the CRM side, and were really targeting the potential renewal cycle that was going to be coming up in '18.
As you now have the salesforce partnership, does that change things?
I'm just trying to think about where the product strategy and cycle is in terms of that upcoming replacement cycle and what you really see the opportunities for you guys over in '18 and '19 on the technology side of IMS?
Ari Bousbib - Chairman, CEO and President
Thank you.
Sandy, you're correct.
When we bought Cegedim and, by the way, acquired or developed internally a number of technology platforms, we intended fully to try and regain some of the market share losses of the historical legacy Cegedim organization.
Just for a reminder, we are #2 in the specifically defined, narrowly defined CRM market.
Cegedim had been #1 historically, going back 5 to 10 years.
And they were in the market through the on-premise heavy, now obsolete, type of platform.
And we had introduced Mobile Intelligence, which was the SaaS-based platform.
However, all the time, as you recall, we -- because we have a wide suite of applications, we saw the need for a new type of offering that would integrate marketing insights with sales data across several platforms and make those interoperable.
Now, in so doing, because we had developed applications on a lot of different platforms and we had internally developed platforms and acquired platforms, in order to integrate all of these applications, the cost to do so and the speed to market were very high.
We decided to replatform everything on a horizontal, existing, off-the-shelf industry platforms.
We considered several options and we ended up building an alliance with [SLDC], with which we are extremely pleased in terms of how it's playing out.
And that alliance, by the way, extends to the clinical space as well.
We believe this will enable us even better to recapture market share, specifically in the CRM business with our upcoming OCE SaaS application.
Again, when a doctor reads a marketing e-mail from a pharma company, the sales rep that visits these doctors doesn't know today that the doctor read the e-mail, because the marketing system and the sales system are not interoperable.
So with our platform, we find when the doctor read the e-mail, whether there was a specific reaction.
We find the rep that has that doctor in that territory.
And if the doctor is in that rep's call log within the next 7 days, we can immediately notify that rep.
Again, it's a much more targeted, precision sales performance that we are looking for.
And it's really the next generation of commercial applications.
And we believe that this will enable us to recapture market share on the tech space.
Operator
Our next question comes from the line of Robert Jones with the company Goldman Sachs.
Robert Patrick Jones - VP
I guess, just to go back to the next-gen bookings.
Sounds like an additional $200 million since the last update, so about 20%, I guess, of this quarter's bookings.
Can you maybe just dig in a little more, Ari, on where these wins are coming from?
Are these existing clients?
Are they clients who've already started to leverage next gen?
Or are they brand new kind of greenfield opportunities?
Just trying to get a better sense of where you're seeing success with the next-gen offering.
Ari Bousbib - Chairman, CEO and President
Well, actually, a couple of those wins that I remember because I've been -- I was personally involved.
Total, I'm going to say about $35 million or $40 million, and they are with previously locked-out accounts.
That is large, top 10 pharma clients with whom the legacy Quintiles organization had done 0 business over the past 10 years -- I think, 11 years actually, one of them.
So the answer is it's coming from all over the place.
I -- we don't have, again, in terms of the pace and the ramp, it's been not quite linear.
It's actually been accelerating if you take out the $120 million large deal that we talked about in the previous quarter, it's a little -- it's over $500 million of awards and it's been accelerating as a proportion of the total bookings.
And it's really all over the place.
EVP wins, it's with locked-out accounts, and it's -- the decent -- from low sized to midsized type of awards.
Andrew Markwick - VP, IR
Thank you for taking the time to join us today, everyone.
And we look forward to speaking with you again on our third quarter 2017 earnings call.
Matt Pfister and I will be available for the rest of the day to take any follow-up questions you might have.
Thank you.
Operator
Ladies and gentlemen, that does conclude the conference call for today.
We thank you for your participation and ask that you please disconnect your line.