Neogenomics Inc (NEO) 2025 Q2 法說會逐字稿

Good morning and welcome to the NeoGenomics second quarter 2025 financial results call. (Operator Instructions) Please be advised that today's conference is being recorded.

I will now turn the call over to Kendra Webster, Vice President of Investor Relations.

Thank you, Tom, and good morning everyone. Welcome to the NeoGenomics second quarter 2025 financial results call. With me today to discuss the results are Tony Zook, Chief Executive Officer; and Jeff Sherman, Chief Financial Officer. Additional members of the management team will be available for the Q&A portion of our call.

This call is being simultaneously webcast, and we will be referring to the slide presentation that has been posted to the investors tab on our website at ir.neogenomics.com. During this call, we will make forward-looking statements regarding our future performance, business strategy, and financial guidance. We caution you that the actual events or results could differ materially from those expressed or implied by the forward-looking statements. These forward-looking statements made during the call speak only as of the original date of this call, and we undertake no obligation to update or revise any of these statements.

Please refer to the information disclosed under the heading risk factors in our most recent Form 10-K, 10-Q, and 8-K that we filed with the SEC to identify important risks and other factors that may cause our actual results to differ from the forward-looking statements. These documents can be found in the Investors section of our website or on the SEC's website.

During this call, we refer to certain non-GAAP financial measures that involve adjustments to GAAP results. The non-GAAP financial measures presented should not be considered an alternative to the financial measures required by GAAP should not be considered measures of liquidity, and are unlikely to be comparable to non-GAAP financial measures provided by other companies.

Any non-GAAP financial measures referenced on this call are reconciled to the most directly comparable GAAP financial measures in a table available in the press release we issued this morning And available in the Investors section of our website.

I will now turn the call over to, Tony.

Thanks, Kendra. Good morning, everyone, and I thank you for joining us today. I'm pleased to leave this call having now completed my first quarter as CEO. Since becoming CEO in April, I've engaged with the business, including sales, operations, and R&D and re-examined our strategic initiatives and financial targets from a more in-depth perspective than I could as a director.

I've also met with existing and potential partners at various industry conferences and had conversations with many of our shareholders to better understand their perspectives. These conversations reinforced the significant opportunities to drive value for our customers, patients, and shareholders.

Cancer testing continues to be a large and attractive market. Most of our business today is in diagnostic testing, though recently, we have accelerated our offerings in therapy selection with the launch of several NGS products. In addition, our radar 1.1 technology and R&D work and next generation MRD enable us to participate in a market that's under penetrated and rapidly growing.

I acknowledge that our delivery this quarter was below expectations. While I remain extremely optimistic about the future of NeoGenomics, our team and I are doubling down on our efforts to focus the business on execution excellence as we build upon our disciplined, financial and operational foundations. But before we talk about our plans moving forward, let's spend time on the quarter.

We had a solid second quarter in the core clinical business, posting significant volume and share gains in key segments. However, our non-clinical revenue was below expectations. Revenue for Q2 was $181 million slightly below our second quarter guidance range, though still representing double digit growth of 10% year-over-year. Our clinical business continues to expand with organic growth at 13%. Strength in our clinical business was offset by continued weakness in our non-clinical revenue, driven by lower revenue from pharma and biotech customers.

In the second quarter, we saw a sequential improvement in AUP, a record quarter for test volumes, and NGS growth at 23%, slightly below our 25% target, but well ahead of the low to mid-teens NGS market growth rate. We can continue to capture market share and clinical revenue, but we made a conscious decision to leverage the learnings from our PanTracer Liquid Biopsy EAP to establish an even stronger product profile for launch. This meant we delayed our launch, which resulted in lower revenue and a lower than targeted NGS growth rate.

I'm excited to confirm that PanTracer Liquid Biopsy will launch commercially tomorrow and believe that our approach to bringing this product to market will positively impact patients treated in the community and our NGS growth rate later this year.

We're projecting lower than planned revenue from pharma customers for the remainder of the year, as well as a negative impact of revenue associated with lower than planned volumes for PanTracer Liquid Biopsy, and NGS mix. As a result, we've updated our 2025 financial guide, which Jeff will provide more insight on in a moment.

I am confident that Neo can continue to achieve double digit annual growth, build product gaps through organic and inorganic activities, and capture additional market share. The leadership team and I have drilled down to align our cost structure with revenues, re-establish our consistent execution, and rebuild credibility with our shareholders.

Investments we are making in operating efficiencies this year, including the LIMS project and digital pathology, position as well to achieve more operating leverage in the back half of this year. I think it's important to spend some time discussing our Q2 results and how we intend to accelerate growth and drive value.

The pharma macro environment conditions contributed to the revenue shortfall in the quarter versus our expectations. Specifically, market uncertainty surrounding NIH funding, drug pricing, patient enrollment in clinical trials, and potential tariffs are leading directly to investment volatility and creating significant headwinds for both our pharmaceutical and biotech clients. This is resulting in budget restrictions, reprioritization, and consolidation of assets, and postponed or canceled projects specific to our pharma services line that are more pronounced than we've experienced over the last two years.

As we've shared in past quarters, radar 1.0 is a growth driver for pharma revenue and also provided a call point to sell other testing modalities. As a result of the negotiated settlement, these radar 1.0 contracts are no longer producing pharma revenue in 2025.

We are adding additional testing capabilities in our portfolio to make our menu more attractive to our pharma and biotech customers, such as [Peletra], our AI-powered spatial proteomics platform, which launched in June. While we have updated our pharma of go to market strategy and made key changes in leadership, it is taking longer than anticipated to yield results.

So how do we plan to respond to these challenges? Our strategic drivers are focused on three areas, the customer experience, the community channel, and new products. Optimizing and winning the customer experience continues to be our competitive strength. We've earned a market leadership position in heme through our heavy investments in community hospitals, and we continue to invest in the community oncology setting. To win the customer experience, we focus on investments in our salesforce effectiveness and efficiency, bi-directional interfaces and ordering portals, as well as automation and digital pathology in the lab.

Last quarter we announced our plans for epic integrations which we believe will begin to impact our revenue in late 2025. We're also continuing our multi-year process of integrating our multiple limbs into one single limbs, which will allow us to sunset eight legacy systems. We believe this will give us operational efficiency, enable us to further improve our turnaround times, and further enhance our data assets to fuel more robust growth in our oncology data solutions business.

In terms of enhancing our community channel strength, we leverage our business development capabilities to establish effective, compelling partnerships like the one with adaptive around delivering industry-leading heme MRD tests to our customers, which we have started to bring the market to a control pilot earlier this month.

Our pipeline of future opportunities continues to grow as we capitalize on the recognized strength and the unique brand recognition of our channel in the community space, coupled with our sales effectiveness. A key growth driver for clinic lymphoma is focusing our R&D and business development efforts on new next-generation precision guided products.

We believe MRD and therapy selection NGS provide the biggest market opportunities and represent the largest associated unmet need. The 30 billion MRD market specifically represents significant unmet clinical needs, particularly in load shedding cancers.

MRD has the potential to transform cancer care by enabling earlier detection of recurrence, more precise treatment decisions, and better outcomes for patients. This also makes MRD highly relevant to biopharma partners to advanced targeted therapies. We intend to make further progress here and evolve our product portfolio to be more comprehensive across the cancer care continuum.

Simultaneously, we will continue building on our deep relationships with the community hospital pathologists and growing relationships with community oncologists, providing us with an even wider competitive moat, and reinforcing our responsibility to inform treatment decisions with actionable insights.

As I mentioned at the outset of this call, I've met with many of our shareholders to better understand their perspectives. They challenged us to rethink our confidence levels and to be transparent in our guidance, incorporating the risks and uncertainties inherent in our industry and our business. We take this feedback seriously, and I want our shareholders to know they have been heard.

Revising our 2025 guidance reflects the headwinds I've discussed while at the same time acknowledging the efforts we've implemented to best position the company for the future. I'm confident we can achieve these forecasts, and if we execute on our action plan, I'm just as confident that there is additional upside we can capture as well. We intend to prove that one quarter at a time.

As a member of the Board of Directors, I approved the update to the long range plan we communicated earlier this year. As CEO, one of my primary objectives has been to oversee the execution of the strategy behind the plan and proactively identify opportunities to improve upon it.

Here's how I think about our long range plan. It's just that long range. While the plan covers the company's execution of certain key metrics during the next five years, this does not guarantee that the plan is going to correlate exactly to our guidance for the coming year, and there will be variability from year to year.

My confidence in the long range plan is based on three key assumptions. First, we believe that the core business, which now includes Pathline, will continue to grow at a 10%-plus rate even with the headwinds affecting our farmer revenue. Second, our business development activities will add incremental revenue that materializes gradually with significant growth in the out years, but the timing will be lumpy depending on deal terms and structures.

Finally, as we increase our investments in R&D and launch PanTracer Liquid Biopsy and future products like NextGen MRD, we expect to generate incremental revenue through consistent improvement in NGS mix and growth. Beyond that, to the extent the farmer headwinds subside, there is an upside.

As we progress into the back half of 2025, we will continue to monitor the impact of the recently passed federal budget bill, changes in the former landscape, and the success of our liquid biopsy launch. Consistent with our historical practice, we will release our 2026 guidance when we report our 2025 full year earnings in February of 2026.

Going forward, like many in our industry, we will not be providing external updates on our progress against the long range plan and will instead focus on our near term guidance targets. Based on my experience these last four months, I'm more optimistic than ever about Neo' future.

And with that, I'll hand it over to Jeff to further discuss our results from the quarter.

Thanks, Tony, and good morning. Second quarter total revenue growth accelerated from Q1 and increased 10% over the prior year to $181 million. Total clinical revenue continued with double digit growth and increased by 16% from prior year. Organic clinical revenue was $160 million, representing growth of 13%, driven by a 10% increase in test volumes and a 3% increase in AUP.

In the second quarter, NGS testing accounted for 32% of total clinical revenue and grew by 23% over a prior year. This strong clinical growth was partially offset by non-clinical revenue, declining by 26% over a prior year, driven by weakness in the farmer revenue Tony spoke about.

The second quarter was also a difficult com with prior year farmer revenue of $18.7 million or 10% higher than the average pharma revenue per quarter in 2024. Adjusted gross profit improved by $4.6 million, or 6% over the prior year. Adjusted EBITDA was $10.7 million, down 2% from prior year while delivering our eighth consecutive quarter of positive adjusted EBITDA. The decrease of due primarily to the acquisition of Pathline as the business is ramping. Excluding Pathline adjusted EBITDA improved by $1.4 million to $12.3 million or 13% from prior year.

Average revenue for clinical tests increased by 2% to $461 from the prior year and increased sequentially from Q1, even with the lower AUP Pathline volume, excluding Pathline AUP grew 3% over prior year due to increased ordering of higher value tests, including NGS and strategic reimbursement initiatives.

As I noted on the first quarter call, we have successfully renegotiated several managed care agreements in the second quarter, which will possibly impact revenue in the second half of 2025. Q2 results include a non-cash impairment charge of $20 million associated with the upcoming replacement of our IVFL test with PanTracer Liquid Biopsy and the write down of repello and assets held for sale.

While we remain focused on 2025, our full year -- our revised full year guidance reflects the challenges of the current farm environment and its impact on customer demand, as well as the delay in launching PanTracer Liquid Biopsy.

At the time of our first quarter earnings call, we believed that clinical would make up for the initially projected $7 million shortfall in pharma, but demand for services has proven to be weaker than anticipated. As a result, the $7 million gap will increase, and we no longer believe that clinical can make up the pharma services shortfall for 2025.

For full year 2025 we now anticipate revenue of $720 million to $726 million, representing 9% to 10% growth for the year with adjusted EBITDA of $41 million and $44 million. The Pathline integration is on track and progressing well with the potential impact to adjust the EBITDA of negative $1 million for the remainder of the year.

We remain well positioned to invest our business and capitalize on the growth opportunities in our strategic plan. We significantly reduced our debt in the second quarter with the retirement of the $201 million convertible notes due in May out of our existing cash. Cash flow from operations in the second quarter was a positive $20 million, an improvement of $6 million or 44% over the prior year, and we ended the quarter with cash and marketable securities of $164 million.

Our balance sheet has no near term debt maturities, and we continue to balance capital deployment between organic growth investments, business development, and improving operating efficiency. Our balanced approach towards capital generation and allocation reflects our commitment to our strategic focus areas. Specifically, our investments will be focused on filling gaps in our broad menu, including ultra sensitive MRD, liquid biopsy, and whole genome sequencing solutions.

We have improved the financial health of our business dramatically over the last several years, and we continue to progress in Q2. We are focused on executing our plan to achieve long-term sustainable and profitable growth and delivering shareholder value. To illustrate our confidence in our strategy and path forward. I, along with Tony, Warren, and additional management team members, as well as several directors on our Board, recently purchased additional shares.

Now I will hand it back to Tony to wrap up.

Thanks, Jeff. To recap, we have strong relationships in the community setting where 80% of cancer patients are treated. Operational capacity and network footprint, and financial discipline and flexibility to expand our reach and generate value for our patients and shareholders alike. We will remain guided by our strategic drivers and committed to our mission and vision, while focusing on generating meaningful growth and enhancing value while improving patient care.

Thank you for your continued interest in NeoGenomics, and now I'll pass it over to Kendra for questions.

Thanks, Tony. All right, Tom, let's go ahead and open the line for questions.

(Operator Instructions)

Andrew Brackman, William Blair.

Hi guys, good morning. Thanks for taking the questions. Tony, maybe to start on setting guidance, we've seen several updates on both near and long term guidance updates so far this year, and this is yet another one. So from a high level perspective and now that you're four months into the CEOC, can you maybe just sort of talk about the process and philosophy or setting guidance, maybe how that's changed, and I guess maybe even more pointed here, what are some of the things that you're committed to doing to rebuild credibility with the investor base? Thanks.

Yeah, thanks Andrew. I do appreciate the question. First off, I guess, what have been my learnings now that I've had the opportunity as you say, to sit in a Chair. I will tell you there is a big difference in seeing the company at a 10,000 foot view as a director versus the opportunity to dig deep as the CEO, and I have had a significant amount of learning.

I've had the opportunity to do deep dives with R&D, with our business development teams, with R&D operations and our commercial groups, and with the management team as well to be able to construct, reconstruct, deconstruct the budgets and long range plans to understand all of the key pieces that underpin that. So that -- I certainly have a deeper understanding of that.

I've had the opportunity to meet with a lot of our investors and get their own feedback, and I can tell you they have not been shy about sharing their own thoughts with us and made it very clear that just hitting a guide is insufficient. That's the same with the myths, and we need to be more realistic, a more balanced approach to how we can fade the business. I've been told that it is absolutely appropriate to speak with confidence on the underpinnings of your core assumptions and to express other areas as upsides. So I think that was a great learning for me as well. So I take that very seriously to heart.

I've had the opportunity as well to speak with a number of our partners and potential partners at ASCO, for example, I could tell you that there have been a real inflow of opportunistic advances by companies to see if we could work together to leverage our strength combined with theirs.

And so it certainly has been a learning. As far as what do I need to do, I think I need to speak with confidence, and be transparent with how we view the business, and to share that openly with people. And the biggest thing, Andrew, we now need to deliver. We missed our revenue guide this quarter, it's unacceptable. We understand that and take responsibility for it, and now moving forward, we just have to hit and exceed our goals quarter on quarter. Does that help?

That's very helpful. Thanks for all that color, Tony. Maybe, what your comments and talking about the underpinnings of core assumptions. Maybe as it relates to 2025 guidance, can you maybe just talk about some of the levers to towards the guide down maybe just bridge the prior guidance to this guidance, in terms of kind of some of the key areas that you talked about. Thanks.

Yeah. I will focus primarily on two of them, Andrew. I mean, mix is always an issue with a company of our size, with the portfolio of our breadth, right? So when you're trying to manage 500 products across a landscape, you are going to see subtle shifts in mix. So that's always an issue for us to manage. But I would say that there were probably two large areas that are reflected in the guide.

First and foremost, the pharma side, the impact of the macro environment came at a speed that I don't think we fully accounted for relative to our original guide. The combination of tariffs with pricing challenges with NIH funding declines, all of those things factored into an environment for our pharma and biotech customers that created uncertainty. And I think that in large part translated into a delay in projects or, reassessment of projects and sometimes stopping of projects.

And so I would tell you that, that is probably the single largest contributor to the change in guidance for the year, probably representing almost two thirds of it. As I said in my opening comments as well, we made a conscious decision to leverage our PanTracer Liquid Biopsy, EAP learnings, and by doing so, I'm glad we did it. I believe we end up with a better product profile, and I believe we took the right requirements to improve that product profile moving forward, but not having PanTracer in the portfolio in May as opposed to, our opportunity to start the commercial launch tomorrow.

We're excited by the launch tomorrow, but that is a three month delay, Andrew, and so that does affect our overall mix and revenue for the year. And then I guess maybe a final piece is, we are quite proud of our NGS penetration rate, we did 23% growth for the month, but I mean for the quarter of it, it's still a little bit behind the 25%, and we acknowledge all those factors, I think in the guide moving forward and not least of which was as well the feedback from some of our shareholders saying speak with confidence. What can you deliver, and if there's opportunity for upside, then surprise us later.

Great. Appreciate the update. Thanks guys.

Thanks, Andrew.

Yuko Oku, Morgan Stanley.

Hello, thank you for taking my question. Given the focus around rolling out the PanTracer or lineup and NGS tests in general being growth driver of the company, do you see opportunities for portfolio pruning? How do you balance being one stop shop for your customers versus focusing on allocating your resources to the most profitable product?

I'm sorry, can you just repeat the last part?

How do you balance being one stop shop for your customers versus allocating your resources to the most profitable products?

Okay. That's a -- it's a great question. First, let's start with PanTracer Liquid Biopsy. As you say, we are looking forward to the launch tomorrow. We believe we have a very competitive product to bring to market. It's one that our customers have actually asked us for, because it compliments that our family of PanTracer products.

There'll be a comprehensive panel over 500 genes, will include TMB and MSI that guides immunotherapies. We've been able to lower our input requirements so that we get better collection methods and yielding strong, very strong TOS profile. We've been able to support a turnaround time that we believe will be less than seven days and I think that factors into a pretty good value proposition for our customers.

And as you say, we look to the depth of the portfolio, and we believe we have solid offerings not just in the PanTracer Liquid Biopsy family of products but across the spectrum of products. Warren, you want?

Yeah. Let me add to that. So first and foremost I'd say that our broad portfolio is absolutely a strength when we think about labs sending out their oncology testing, they're looking to consolidate vendors that they want to send their testing to, and this puts NeoGenomics in a very unique position. That we're able to address most of their needs.

Having said that, yes, our strategy is to protect our position on the diagnosis side, but invest significantly in therapy selection and MRD, which are the areas where we see foster growth larger TAMs. So with that, we definitely see opportunities to simplify the portfolio which we have done in 2025 and we will continue to do for the rest of the year and into the future, but our strategy is to provide a holistic solution to our oncology physicians from a diagnosis perspective therapy selection, and MRD point of view.

And then I would say from an overall portfolio perspective you should expect we're continuing to evaluate the whole portfolio and Warren said it's an ongoing process of pruning and refining, based upon customer needs.

Great, thank you for that color. And then a follow up question, could you also provide us with an update regarding radar ID litigation? I think there was a recent order on motion to expedite. What does it mean for the trial expected to occur, I think in the October time frame.

Yeah. First, relative to the litigation, again, you can appreciate this. I'm not going to go into detail, no members of the team with any ongoing litigation. What I can update you on is that the trial is slated for October. Either way, I can tell you though, we are committed to the MRD space. As you've seen, we are partnering with Adaptive to bring forward a great MRD heme product into the marketplace, and we're proud to do that.

We get benefit from that by being in the marketplace and taking those learnings and the added benefits to the rest of our portfolio. We're going to continue to invest in our NextGen MRD. So that is built into our R&D plans moving forward. We have done our preparatory work behind the scenes, so we have completed and submitted our bridging study to MDX, and we are doing all the prep work we need for launch. And so I will tell you that we are prepared and ready.

Now recently [Nutera] has filed a motion for a bench trial. We oppose that motion. We believe that we have a constitutional right under the 7th Amendment for jury trial, and the court has yet to rule on that motion. So, I would tell you, stay tuned, you'll know when we know, but we are coming into this space and we are committed to this space.

Thank you.

You're welcome.

Subbu Nambi, Guggenheim Securities.

Hi, this is Thomas Bonneville on for Subbu. Thanks for taking the questions. Just to start, can you get us comfortable with the second half of ramp, specifically with NGS now that PanTracer was delayed a bit, and also with the continued pharma pressures, where do you feel the guide is most aggressive still and where is it most de-risked?

I actually think that we have a much more confident and balanced guide in the second half. I would tell you the greatest risk to the guide was on the pharma side, and so we have further reduced the pharma business plan, and by the way, not just in revenue, we've also taken some hard decisions relative to the cost base associated with pharma as well. So I would tell you that was the largest risk to the plan. As far as the biggest growth drivers in the plan for the second half, as you know, we've invested in our selling force and we monitor that very closely.

We expect to see increased effectiveness and efficiency with that investment in the sales force to help us further penetrate the NGS segment. Certainly PanTracer Liquid Biopsy plays a big role in the second half, in addition to just the normal back half year increase that we see historically, the adaptive partnership is also an opportunity for us in the second half of the year, and I would also tell you that we are well on plan with our Pathline immigration, and that started first and foremost with just getting integration correct, getting it done right and making sure that there were no hiccups along the way, but as you will recall, that was of more strategic value to us, and we want to see the opportunity to further drive share of our ongoing business in the second half of the year up into the Northeast. And so Beth and Warren on their commercial teams are focusing hard there.

And then finally, we are working hard on interfaces with our customer base. We think that, that has an opportunity for us in the second half of the year as well because when those interfaces go live, you have a better opportunity for increased penetration because it just makes it so much easier for customers to do business across our portfolio. So thanks for the question.

Thank you. And then just for my follow up last quarter you talked about, I think it was five products meaningfully contributing to NGS revenue. Did you have a similar concentration this quarter? And can you talk about if you expect that to evolve at all over the, balance of the year? Thank you.

Yeah. We -- thanks again for the follow up. We do expect it to evolve. We expect it to evolve and increase. The pi concentrated products that we spoke to, we talked about their ability that they represented almost 21% of our clinical revenue that has continued to grow, and we saw in this quarter that's up to about 23%. And relative to the broader business, all of our NGS products are now have eclipsed about 30% of our total revenue. And so, this is an important growth driver for us. We monitor it closely, and it's one of the biggest opportunities for us over the medium and long term as well. So thanks for the follow up.

Mike Matson, Needham & Company.

Yeah. Thanks. So just want to clarify that the comments on the long range plan. So you're talking about double digit growth now. So is that -- are you just to be clear, are you backing off the 12% to 13% target on the set earlier this year and so you're expecting kind of 10%-plus over the next few years?

Yeah, Mike, thanks for the question. What I am -- first off, we are not backing off of our long range plan, but what I am trying to do, Mike, is create added transparency so that there is no ambiguity of what is in it and how I view the business. And so that's why I'm trying to drive for more clarity.

My conversations with investors, they asked for that because what's in, what's out, and how do you get there from here was a big question for them. So let me once again just reiterate it if you don't mind, so that everybody can be clear.

I look at this as our base business today. What do we have in our bag to sell, to bring to our customers now? That is a proven. I have it. That based business, in my mind, that is a 10% growth business over the planning period. So that is our anchor position.

Now you've heard us talk time and time again. We are not standing still as we sit here today. We are investing. We're doing it responsibly, but we are investing in R&D. We do plan to have more products and therapy selection and MRD, and those opportunities create incremental value above that base plan, and I'm acknowledging that, that comes later in the cycle, right? That's -- there's a lot of things we can do. I can't compress the time continuum and so those just come later in the cycle.

And then the other area that we're not going to stand still on is business development. We believe that there are plenty of opportunities for us to supplement our portfolio. We have seen that they can add incremental growth into our business in top and bottom line performance, but I also acknowledge that they're lumpy. You can't predict the exact time of those.

So from my vantage point, the long range plan starts with your anchor position of the 10% growth in our current portfolio. We build from there with business development and of course new product development, and that's the plan. I also want to just reemphasize that to me the long range plan is just that. It's a long range plan. It is never intended to be a forecasting vehicle for any given year, and I plan to deemphasize these conversations around the long range plan just like our peers do.

I'm going to focus our energies on our short-term delivery. What can we deliver quarter over quarter and in that given year and not be focusing our energies and discussion points around a long range plan. That helpful?

Yeah, that definitely makes a lot clearer. And then just on the non-clinical business, I mean, given the steep declines we're seeing now. I mean, would it be possible to exit that business? Is there some kind of synergies with the clinical side and then, what would that -- how profitable is that part of the business because it may be an issue where, more profitable than the clinical side and then, you'd be giving -- it'd be hitting the bottom line too hard if you were to exit it.

Yeah. Thanks again for the follow up. I'm like -- are there synergies across the lines that the answer for the operations team is yes, there are opportunities for that. But I think the bigger question is, are we committed to the space, right? And I can tell you that we are. We do believe in the space. It is of strategic value to us.

It provides the opportunity for us to identify and to validate biomarkers early. It provides the possibility of the development of companion diagnostics. It keeps us at the forefront of emerging technologies so that we can stay not just current but a step ahead of where we want to take our own activities. It also does play a role, Mike, in accelerating the launch of new products, right? You don't have the same reimbursement hurdles in that space that you might across other parts of the business.

And so we believe in the pharma space over time that it does help create value, but I also need to be reflective of the short term impact to that, and we have adjusted our revenue lines there, and I do not personally anticipate that these changes in the environment are going to subside anytime soon, and we reflected that in our business plan moving forward.

Yeah. And I would add to that, I think you know we still have excess capacity, in our footprint as well as continuing as we've talked about our lens integration, which will allow us to increase our operating efficiency for our form of business as well.

We don't break it out separately now, but we used to break out advanced diagnostics previously and prior periods. And it had a lower margin profile overall than the company, but as we look at excess capacity, the business development and R&D opportunities, as Tony spoke about and then if the limbs work, we still think it -- it's going to be a viable business for us going forward and we think that we'll be, a plot out at some point in the future which we can build upon from a growing perspective.

Okay. Understand. Thank you.

Mark Massaro, BTIG.

Hey guys, this is Vivian. I'm for Mark. Thanks for taking the questions. So maybe just one Pathline, just help us understand how the contribution in the quarter, was tracking relative to your internal expectations, and then I know you've cited an intended benefit of cross-selling, the broader portfolio with Pathline customers, in the past, so just curious, how you're seeing that dynamic play out. Thanks.

Sure, I'll be happy to start that, and Warren can jump in anytime. As far as the integration and the intended results versus actual, we are right on plan with the Pathline integration. The revenues were right in line with our expectations, and so we feel very, very good about the shape of that acquisition and the shape of the business, as you rightfully say, it's not just a business benefit relative to Pathline alone. There was strategic value associated with the acquisition.

We saw the opportunity to enhance our footprint and therefore our speed of delivery to key customers in certain segments of our market in the Northeast. And so it is our plan to continue to drive the current Pathline business, but as well take advantage of our more in-depth portfolio and bring NGS products up and through into the Northeast, with greater rigor and speed that was always intended to take place in the latter half of this year with that benefit being more realized in 2026. And of course we will do everything in our power to pull as much of that forward as possible and I'll look at more if you want to add some additional color.

Yeah. Thanks, Tony. You covered most of the key points. I think one of the key elements for us to really enable this capability in the Northeast was to further validate tests within this lab, and that was always plan to take place in the second quarter. And again, just to remind everybody, we closed this this acquisition in the early part of the second quarter as well.

So we've actually concluded the validation requirements for these additional tests that we wanted to move into the Northeast to round out the portfolio that's required in that lab, and now we are actively addressing sort of these opportunities to drive additional share of wallets and pull through. The sort of opportunity funnel looks robust and certainly expect to see many of those come to fruition in the second half of the year. And as Tony said, that would be an upside for us in the second half and certainly something that would drive material value for us in 2026 and beyond.

Thank you.

David Westenberg, Piper Sandler.

Thank you for taking the question. So I actually wanted to talk about the 10% volume growth and that was organic, I believe. And can you talk about what that might mean for share gains and versus the market? Can you give us any context to what historical volume growth is in the market, help us really evaluate the overall strength in the business.

Well, I would say first and foremost as you rightfully note the growth was 10%. Across our business we have made good growth, across all the various modalities. So we continue a storyline that while our focus has been in NGS and making sure that we grow that important segment of our business, in fact, across all of our modalities we continue to make great progress and we see share gains across all the modalities.

And so it's quite a positive for us moving forward. As you also rightfully have seen in the earnings release, it's also record high volumes for us across the business. And so, for us, we see the opportunity to continue to grow volume. We do see the opportunity to grow share in our key segments, and that is what we are focused in doing.

And I would say if you look at it from a modality perspective, we're seeing growth rates, in modality in the 2% to 3% to 5% range, and I would say kind of across the board we're growing significantly faster than that.

Maybe I want to build on that just from a commercial execution perspective and I think the development from a volume perspective is testament to a strong commercial strategy well executed. And coming back to the fact that we have our territory business managers that are looking at the pathology business. And the oncology sales specialist looking more at the community oncologist from a therapy selection point of view.

That really drives towards providing a solution to these ordering positions. And although we do prioritize certain products, it's very much around providing a holistic solution across their needs. And this is what's driving the incremental volume across all modalities, and we're seeing growth, greater the market, as Jeff and Tony said against each of the modalities, but we do over index on NGS because of the desire to move to the right into therapy selection, as well, and we do that through sort of incentive compensation and other focusing mechanisms, but it really is the testing of a strong commercial strategy being well executed, that seeing this volume growth across all modalities.

And I think seeing 0.3% NGS growth without our liquid biopsy product is again continuing to see very strong growth there above market growth there and now adding what we believe to be a very new and important product is going to help drive more growth in the back half of the year.

Perfect. And then if we, I mean, I know you're not giving second -- 2026 guidance, but if you can maybe talk, long term, Tony, about how you think about operating margins in '26 and beyond, is there any kind of, planning on growing EBITDA up faster than revenue in in the years out? Is that kind of the mission here? And then back to Jeff, can you talk about some of this cash flow and operating margin seasonality that you kind of see in the business and I'll take it from there. Thank you.

Well, I will obviously wait for '26 to talk about '26, which we will do in February, but to just give you a sense over the longer term plan, do we still see that there is operating leverage for us as an organization? The answer to that is yes. We will continue to make the right investments in our operations sites. We have made a really good progress with the LIMS project and we look forward to having a com one common limb system and we can retiree legacy systems.

There are opportunities for us to do the same thing, in a number of different areas through automation, through digital pathology, so we do expect that we can increase efficiencies and effectiveness in our margins. And that in turn will lead to solid growth over time. And we also believe that there are going to be some midterm opportunities for us that we'll talk about in more detail that we can create more value for the company.

We have a strong financial discipline embed in the company. We're going to build on that and we do see plenty of opportunities for us to continue to cost, reduce, find efficiencies and improve margins.

Yeah, I would add to that, and I would still characterize we think we're in the early innings of really capitalizing on both, the LIMS integration as well as, investing in automation and really think we have an opportunity to drive operating efficiencies there. And then from a cash flow perspective, generally Q1 is our biggest cash burn and that played out again this year and we start building from there. So we had a very strong, cash to quarter actually. Free cash flow positive this quarter and as I said in my prepared marks cash flow from operations was up over 40% in the second quarter.

We are still very focused on revenue cycle management. And making sure we're collecting, what we generate from a revenue perspective and expect that cash balance will build as the year progresses with the with the normal seasonality with the back half growth or expecting that that we've seen historically.

Thank you.

Dan Brennan, TD Securities.

Great, thank you. Thanks for the questions. Maybe just one to start on the non-clinical business, it's been a kind of continued weak spot for you. I think it was down -- I think you said 26% in the second quarter. I know you don't break out guidance, but just to ideally remove or minimize the risk that, kind of more shortfalls here, kind of depressed results in the back half of the year end or the stock, is down 40%, 50%. Like how can you help us frame any sense of how we think about the back half year, kind of what's baked into the new guidance, like if we punching down 50%, we would get to the midpoint of your range, not changing our clinical assumptions. I'm just wondering if you can help us do that bridge.

Yeah. I think on the pharma side I would expect a similar performance as we had in the first half of the year. We generally see a little bit stronger performance in the fourth quarter in our data business, our ODS business, so I would expect that as well. But pretty consistent with the first half with some upside in our ODS business in the fourth quarter is how I'd characterize, what we're contemplating.

Okay, and then the PanTracer side, did you -- and I'm sorry if I missed this, did you give an update on where reimbursement stands? Then I know you talked about you delayed the launch due to learning from the EAP, so could you share any insights from it?

Dan, what I would tell you is that we are in ongoing conversations with Multi-X, and we will share the final outcomes of those. We are confident in our path forward towards reimbursement and that's why we are launching tomorrow.

Got it. And anything on the learnings in terms of the EAP, Tony, and did you guys break out how to think about kind of what you've put in the contribution for the back half a year, ideally it's kind of modest to give you room for beats, but just kind of wondering on those two factors.

Yeah. We haven't given a specific forecast for PanTracer in the second half of the year relative to the learnings, Dan, I think we found that there was an opportunity for us to improve the profile of the product. We're excited by it. We'll have a very low Q&S profile. We have verified a really exciting turnaround time that our customers are going to welcome and we believe that we have a very comprehensive test that we bring forward.

And so for us it was the right decision to take, and we feel more confident about when PanTracer hits the market. But as far as specific ramp ups, I don't think we're going to be talking about that direct.

Yeah. I would just add, it's a new product, so it will incorporate a new product range.

Yeah.

Yeah. And Dan, maybe just adding to, I think once we the sort of the revised EAP that we went live with Fed probably a month ago or so, the demand that we saw with the revised target product profile was significant and very encouraging in terms of what we expect to see post commercial launch tomorrow.

Got it. And I know there was one question on MRD, I know you discussed [Nutera] looking to have a jury trial. Could you just remind us -- would you mind just kind of zooming out since the next quarter in the back half of you we're going to get some of these key events on your MRD strategy, whether or not you can kind of launch with your existing platform and to move on, just kind of could you just reframe how to think about the various outcomes as we move into the back half of the year on MRD.

Well, again, what I would tell you, there are some things that are more concrete than others, right? What we will definitely be doing in the second half of the year is our adaptive partnership with heme MRD. We are in the early days of a pilot with Adaptive. We want to make sure that the partnership is seamless to our customers and that we've tested everything end to end. So that is going to happen. We are working through those pilots now and we look forward to a more complete launch where both companies are satisfied that our customers see this as a great partnership and that should be closer to the back half of the year.

Relative to the radar litigation, I would tell you that, right now, the trial is slated for October, I can't speculate on, what the results will be or when they will be, I can tell you that we have done all the back office work in preparation to be able to launch. So our bridging work and everything has been submitted. So all of that is on track. I would remind everyone that we didn't have any of those radar revenues in our guide nor in our plan. So if we are successful there, that represents upside.

And another area that we are doing, Dan, we are investing in next generation MRD with Andrew and his team. We said that, this would be a year where we're really specking those out. '26 would be a year of more active product development, and we look forward to those market opportunities in '27 and beyond. So that's kind of what I can give to you relative to MRD landscapes.

Perfect. Great. Thanks.

You're welcome, Dan.

Tycho Peterson, Jefferies.

Hi team, this is Lauren on for Tycho. A quick one from me going back to the NGS growth, you guys talked about how you achieved 23% regardless of the delay in the commercial launch with PanTracer. Could you talk a little bit about how much of that is being driven by test mix shift versus true market expansion and kind of how sustainable that cadence is into 2026. Thanks.

The majority of it is true market expansion. I mean, naturally, there is a mixed benefits and it's common knowledge that the NGS has a higher AUP than the rest of our portfolio, but if you look at true sort of volume growth, that remind significantly higher than what we're experiencing from -- what we see from a market growth perspective.

And really again it comes back to the commercial strategy where we have our dedicated sales team of oncology sales specialists who spend the majority of their time. Focused on the sale of NGS related products within the therapy selection, part of the business. And again, we're gaining traction in this space and this is really what's driving these share gains that we are seeing and we believe the addition of PanTracer liquid as of tomorrow will further accentuate that.

Great. Thank you.

Michael Ryskin, Bank of America.

Great, thanks for squeezing me in, guys. I got, just a couple small follow-ups on topics that people touched on before, so hopefully really rapid fire. One is, on PanTracer, so just kind of confirming that no change to your planned ramp or planned execution the first couple of months or first couple quarters out of the gate, there's a delay, but the plan going forward is the same and nothing's really changed on that.

Yeah. From point of launch, the plan remains the same, but of course that point of launch had experienced about a three month delay.

Okay. Just making sure. Then on the part of services, I mean, totally hear you on what you're seeing in the market and, yeah, not surprising given what we've seen elsewhere, but still the results have lagged some of the others in the space a little bit and we just haven't seen the same extent of weakness and it is a little bit more protracted.

So I was just wondering if you could comment on your competitive positioning there. It is a relatively crowded market and there's more and more players offering some of these services. So could you just sort of analyze your portfolio and your offer -- maybe there's something there that, that you're missing on pharma services, or maybe from the commercial side.

Yeah. Relative to pharma, I think, as I had mentioned earlier, I think portfolio does play a role. Our inability to sell radar certainly led to radar 1.0 was certainly led to some of this falloff in revenue and our inability to have a kind of a launch point within those discussions, I think is real. So portfolio does have a role, and that's why we were excited to bring [Paletra] into the marketplace. But Michael, we also recognize that these are long selling cycles and so while there might be some early signs there that look encouraging, I don't believe that they're going to meaningfully impact our shape for their -- the short term.

And as you talk with other companies, yeah, I would tell you that there will be differences by companies. A lot depends on what are the services that they are bringing forward. Some companies have CROs. Some companies do different types of mixes. I can only react to our portfolio, and in our portfolio I see risk in that form of business this year, and I don't anticipate that we're going to see any leveraging or any deleveraging of those issues for the remainder of this year and into 2026.

Okay, thanks. And then the last one, if I could squeeze them more in would be on the cash balance and just sort of feature uses of cash. I know you use the $200 million each quarter to pay down the current part of the converts as you previously talked about, but, you still got a sizeable chunk of the convert going forward.

And now you've got this revised fiscal year, guide. I know, there's a near term versus long term dynamic. Just talk us through cash balance going forward, just confidence in the in the runway for the next couple of years as you get to that, the remaining $350 million on the convert. Thanks.

Yeah, we expect that we'll be generating pre-cash flow next year still, and the cash balance will grow consistent with our earnings growth over the plan. So certainly we have a lot of confidence that we will continue to delever as our earnings increase and we'll be in a very strong position in the future to deal with the 2028 converts, from a position of strength.

Okay, thanks.

Mason Carrico, Stevens Inc.

Hey guys. Two from me here. One, it seems like Pathline may have outperformed slightly in the quarter and sorry if I missed this in the first question, but could you update us on your expectations for Pathline revenue this year and whether the contribution built into guidance has changed at all?

Yeah. We haven't -- I would say Pathline -- I would say performed, slightly ahead of our initial expectations, but we haven't -- we're not changing, the overall guidance for Pathline.

Got it. And then on the pharma side, how much visibility do you typically have in that business in terms of revenue flowing through? Is it a single quarter, two quarters? How is that visibility changed given the backdrop? And could you just talk to your confidence in that segment being adequately de-risked this year?

Yeah. I think I'll add to that. I think the, it is a challenging space, especially with a big part of our business, US based and lots of uncertainty with regards to patient enrollments within the US clinical trials, and that really limits the line of sight that we've got. So it's less than a quarter, believe it or not, in terms of if you want a high degree of accuracy and it rapidly erodes if you go beyond that and I think that's why we've taken a pretty conservative or prudent approach to the forecast for the remainder of this year for the pharma services business.

Got it. Thanks.

Andrew Cooper, Raymond James.

Hey everybody, thanks for the question. A lot's already asked, so maybe just a little more kind of diving into the guidance math. I think Tony, you talked about, a $30 million revenue cut about two third or almost two third from pharma. So there's an incremental $10 million or $12 million that's coming from that's coming from clinical part presumably PanTracer, but I know that's not the full amount. So is there anything else explicit to think about in terms of that step back or is this, hey, we really just want to de-risk, we want to make sure we're in a good spot as the second half of the year plays out.

Yeah, I would say, Andrew, we certainly have heard and we want to make sure that we give you with confidence what we believe we can deliver. And so, that does factor in, but I would tell you that the pharma, as you mentioned, rightfully so the delay in PanTracer liquid biopsy that does contribute to that remaining piece and there's a slight mix effect that also would be there, and I'll ask Jeffy wants to add anything.

Yeah. Just within NGS, the mix of testing between blood versus solid tumor can change from quarter to quarter and so I think where we're seeing growth in -- with some lower modalities from the NGS side, lower growth modalities. So I think that's just that mixed element, hard to predict quarter to quarter, but with the overall growth growing 23%, still think we're going to see good growth there, but the mix will impact the revenue as well play out the rest of the year.

Okay, thanks. And then maybe just lastly, I think Dan tried to ask on this, but can you give us sort of an explicit what the updated PanTracer LVX looks like relative to the initial product that you did in that first EAP? Is it the turnaround time that improved? Is it QNS? Is it both? And kind of how we think about -- are you matching what's out there competitively? Do you feel like this latest iteration puts you ahead and if so on what particular metrics?

Yes. So I'll build on that. I think there was a number of benefits. First of all, we were able to lower our sort of input threshold, that allowed us to reduce the QNS TMP levels that we were experiencing. In addition to that by optimizing the workflow, we were able to accelerate turnaround time, so we're able to offer a significant below the published turnaround time through the EAP, which was really encouraging.

And we also got feedback from select customers through the EAP that we were picking up certain genes that were being missed by a number of sort of peers or competitors out of the marketplace. So really a lot of very positive insights that came from that and as Tony said, we believe that the three month delay is going to be well worth it in the long run.

Perfect. I'll stop there. Thank you.

Thanks, Andrew.

John Wilkin, Craig Hallam.

Yeah. I guess I'll try and keep this really quick, but if my math is right, it looks like your volume for clinical excluding NGS and excluding Pathline actually accelerate a little bit in the quarter. So just wondering if you could talk at all about what's driving that, if there's anything underappreciated in that.

Again, I think it comes back to a commercial strategy that's being effectively executed, seeing the value of the commercial investments that we've made and some productivity ramps. We did speak about early in the first quarter that there was a few new client wins, that we had recorded and obviously those that ran through the last quarter or so and that covers the entire portfolio that we're making available to us, which again I think speaks to the value of NeoGenomics and the breadth of portfolio.

Perfect. That's all. Thanks guys.

Puneet Souda, Leerink.

Yeah. Hi guys. Thanks for the questions here. So first one, could you elaborate a bit on the size of the oncology sales force now and how do you -- what's your strategy in continuing to compete in that market? How much of the NGS sales is sort of coming from the oncologist's channel versus the pathologist's channel maybe just help us understand that and largely because the competition here is only rising when it comes to therapy selection.

You have one competitor that raise capital in the public offering, you have liquid competitors that are now launching tissue and then there are existing incumbents there. So just given all the landscape of that market, what's your NGS growth longer term and then could you elaborate on the oncology salesforce side?

Warren, you want to just talk a little bit about size. I would like to address this stickiness question as well.

Yeah. I think we have executed against exactly the plan that we had spoken about in late last year beginning of this year, getting our sales team to roughly 135 people and sort of 40% of those resources fall within the oncology sales specialist side of things. The greater majority of the growth that we're seeing actually is being driven by that sales team, so coming from the therapy selection side of the business.

There is some that comes through the pathology channel, et cetera. But that's the minority portion. And actually when we speak about these new products that contributed 23% of the business in Q2, the majority of that business too is coming from the OSS side of the business. So despite the increasing competitive landscape, we certainly continue to penetrate effectively and we believe this sort of 25% or so percent growth rate that we put out there still is very much attainable, especially when we launch PanTracer Liquid tomorrow.

Yeah. I just build on Warren's point with you had mentioned that these are competitive markets and others have invested in those markets, and we are not naive to that. We truly appreciate that, the innovators do have a degree of stickiness because they were able to get into the market first, but I was at one of the recent conferences and I reminded people that there are other ways to create stickiness too.

And that is, we bring to the dance, a broad portfolio. We meet customer needs across a number of different areas. We continue to invest in those relationships and we continue to invest in making it easy to do business with NeoGenomics, and that also comes with a degree of stickiness.

And so, we respect our competitors, we respect their innovation, but we also are hungry to get into those segments and we have demonstrated over time that if we have a competitive profile product that we bring to market, even if it lags in time, we have been able to sufficiently grow those businesses. And so we believe in the profile that we have with PanTracer and the PanTracer family and respect our competitors, but believe we can grow in that environment.

And then the focus on operational execution turnaround time continuing to improve as well, I think, has allowed us to grow and retain market share.

Got it. That's helpful. And then, on the OpEx side, if I could you clarify if you're expecting and apologize if I missed this, if you're expecting any OpEx cuts in the guide for this year, and I don't know if you can talk about next year yet.

Yeah. We're not talking about next year yet. I think, we continue to achieve operating efficiencies and expect -- we'll see some operating efficiencies in the back half of the year, and I think there's -- we have a high focus on continuing to see improvements there.

Okay. Thank you.

Thank you.

Thank you. This does conclude today's question and answer session. I would now like to turn the floor back to Tony Zook for closing comments.

I would just like to thank everybody for joining us on the call. I do appreciate the direct questions and the opportunity to present our results and as well our direction moving forward.

I would like to remind everyone though that we did -- do a pretty good job on that clinical side. We grew that business 16%. We had a quarter for volumes, really exciting NGS growth rate, and we are poised to continue to drive performance in the second half of the year. And as Andrew opened the call, I will close it. It's up to us to now deliver quarter on quarter and regain that confidence in our delivery. So thank you for the time and we'll look forward to other conversations.

Thank you. This does conclude today's conference call. You may disconnect at this time and have a wonderful day. Thank you once again for your participation.