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Operator
Good day ladies and gentlemen and welcome to the Quarter Four and full-year 2012 Bio-Rad Laboratories Inc. earnings conference call. My name is Ian. I will be your operator for today.
At this time, all participants are in listen-only mode. We will conduct a question-and-answer session toward the end of the conference. (Operator Instructions). As a reminder, the call is being recorded for replay purposes.
I would like to turn the call over to Mister Ron Hutton, who is the Treasurer. Please proceed.
Ron Hutton - Treasurer
Thank you Ian. Before we begin the call, I would like to caution everyone that we will be making forward-looking statements about management's goals, plans, and expectations. Because our actual results may differ materially from these plans and expectations, I encourage you to review our filings with the SEC where we discuss in detail the risk factors in our business. The Company does not intend to update any forward-looking statements made during the call today.
With that, I'd like to turn the call over to Christine Tsingos, Executive Vice President and Chief Financial officer.
Christine Tsingos - VP, CFO
Thanks Ron. Good afternoon everyone and thank you for joining us. Today, we will review the fourth-quarter and full-year financial results for 2012 as well as provide some insight into our thinking for 2013.
Let's start with a review of the quarterly results. We are pleased to report that net sales for the fourth quarter of fiscal 2012 were a record $573.8 million, an increase of 4.3% versus the year-ago period sales of $550.2 million. On a currency neutral basis, quarterly sales grew an impressive 6.1%.
During the quarter, we experienced good currency neutral sales growth in our diabetes monitoring, quality control and Bio-Plex 2200 product lines as well as many of our life science product lines, most notably process chromatography, amplification consumables, and sales of our QX100 digital PCR system. The overall quarterly growth was tempered somewhat by continued sluggishness in Europe.
The consolidated gross margin for the quarter was in line with expectations at 55.9% and compares to last year's gross margin of 56.5%. The decline in margin versus last year is primarily reflective of product mix, increased amortization costs and continued pricing pressure.
During the quarter, we recorded a total of approximately $6.9 million in cost of goods sold for the non-cash purchase accounting expense related to prior acquisitions, which compares to $6.2 million in the year-ago period.
SG&A expense for the fourth quarter was $189.1 million, or 32.9% of sales, compared to $175 million or 31.8% of sales last year. The increase in spend versus last year is partially related to our ERP project, but also reflective of the one-time reversal of our incentive bonus accruals of approximately $9 million that occurred in the fourth quarter of last year. Amortization of intangibles related to our acquisitions recorded in SG&A in the fourth quarter was approximately $2.4 million.
Research and development expense in Q4 was 10.4% of sales or $59.8 million. This increase in spending both sequentially and year-over-year is reflective of our investments in digital PCR and cell biology products, as well as a focus on the development of new products for diagnostic markets such as diabetes monitoring and blood typing.
Interest and Other for the quarter was a net expense of approximately $6.2 million compared to $12 million last year. This lower expense amount versus last year is related to a one-time gain of approximately $4.3 million for the sale of a building and land as well as increased investment income.
The effective tax rate used in the fourth quarter was 28% and in line with our guidance. Remember that last year's lower rate of 20% was primarily related to the finalization for an audit as well as decreases in tax reserves due to statute lapses.
Reported net income for the fourth quarter was $47.5 million or $1.65 per share on a fully diluted basis compared to $59.2 million last year or $2.08 per share. Excluding the one-time gains for the sale of real property, we estimate that fully diluted earnings per share would have been $1.57.
Our Life Science group reported record sales for the fourth quarter of $204.2 million, a growth of 2.7% versus last year, which was also a very strong quarter for the Group. On a currency neutral basis, sales increased 3.7% for the quarter. These quarterly results reflect strong sales of amplification reagents, process media and continued growth of our new Digital PCR system.
On a geographic basis, sales in Latin America and the US were especially robust. Strength in the topline combined with good expense management helped to push segment profit for the Life Science group significantly higher when compared to the first three individual quarters of 2012.
Our Clinical Diagnostics group also achieved record sales for the quarter of $365.9 million compared to $347.3 million last year, an increase of 5.3% on a reported basis, or an impressive 7.5% currency neutral. These sales were led by continued strong performance in the quality controls and diabetes product lines as well as solid growth for microbiology and Bio-Plex 2200 revenue.
On a geographic view, diagnostic currency neutral sales for the quarter increased most notably in Asia Pacific and North America but were somewhat offset by a continued decline in Europe. Reported fourth-quarter segment profit for Diagnostics also remains strong at more than $51 million.
Looking at the full-year results, we are pleased to report annual revenues of $2.069 billion, about flat with last year on a reported basis. On a currency neutral basis, sales for the year grew 3.6%, which represents a currency headwind of more than $79 million. The organic currency neutral growth for the full year was 3.1%.
With a challenging global funding environment, our Life Science group posted annual sales of $688.4 million, a decrease of about 1% versus 2011 and a growth of 1.5% currency neutral. This sales growth was primarily fueled by our Digital PCR product line which finished the year slightly lower than our original guidance.
We also saw good annual growth in our process media, amplification consumables and electrophoresis product lines, as well as good growth in the Latin America and Asia-Pacific regions. During the year, we introduced several new platforms and consumables which bode well for future growth. Moreover, the recent launches of the new S3 Cell Sorter and our next-generation chromatography system, coupled with the addition of the Serotec antibody business should help to broaden our reach into the tools market around the world during 2013.
For the year, Clinical Diagnostics sales were $1.365 billion, slightly higher than 2011 on a reported basis and an increase of 4.7% on a currency neutral basis. This growth was fueled by continued momentum in quality controls and diabetes monitoring products.
On a geographical view, Asia-Pacific and other emerging markets, such as Latin America, Eastern Europe, showed good growth for the year. This growth was partially offset by a decline in Europe, our largest market.
Total Company gross margins for the full year were 56.1%, in line with our original guidance set at the beginning of the year and compares to 56.8% in 2011. The decrease in margin versus last year is primarily related to the addition of $10 million of acquisition-related amortization expense in our Life Science segment. Total amortization of intangibles and purchase accounting reported in cost of goods sold in 2012 was $26.8 million.
SG&A expense as a percent of sales was 33% for the year and better than we estimated at the beginning of 2012. The two primary drivers of this better than expected margin resulted from the accounting reversal recorded during the year for the $16 million reduction in the Quantalife earnout valuation as sales were lower than expected as well as the bad debt allowance reduction of more than $6 million following unexpected payment from the government of Spain. Excluding these two non-cash items, the SG&A margin for the year was approximately 34%. SG&A expense for acquisition related amortization was $11.7 million for the full year.
Research and development expense in 2012 was substantially higher at $214 million or 10.3% of sales. This increase is a direct reflection of our investment in Digital PCR and cell biology, as well as new product development in the Diagnostics segment. Looking to 2013, R&D expenses as a percentage of sales will likely stay at that 10% level as we move a number of investments through the product development pipeline.
Net income for the full year was $169.2 million, versus last year's net income of $178.2 million, a decrease of about 5%. As we guided at the beginning of the year, the decline in net profit primarily relates to our investment in new IT systems and the addition of Quantalife.
The effective tax rate for the full year was 27%. For 2013, we expect the effective tax rate, excluding any discrete items that may occur, will be in the 27% to 29% range. This estimated rate includes the impact of the retroactive reinstatement of the 2012 federal R&D credit which is estimated to benefit our affective rate by approximately 1% for the full 2013 year, and around 5% in the first quarter.
For 2012, Bio-Rad's balance sheet also remains strong. As of December 31, total cash and short-term investments were $921 million, compared to $813 million at the end of last year. Net cash generated from operations during the fourth quarter was $98.7 million and $278.9 million for the full year 2012. The year-over-year increase in cash flow is a result of higher collections and investment income as well as lower interest payments.
EBITDA grew to record levels for 2012, finishing the year at more than $411 million. Net capital expenditures were $34 million for the quarter and $146.1 million for the full year, slightly above the $130 million to $140 million range estimated at the beginning of 2012 and driven by better-than-expected instrument placements in our Diagnostics market. The decrease in fourth quarter net CapEx is primarily related to our one-time gain on the sale of real property. Looking to 2013, we estimate that CapEx spending will continue in the $140 million to $150 million range, primarily reflecting our continuing investment in new IT systems and technology.
Finally, depreciation and amortization for the quarter was $35.5 million and $130 million for the full year.
We are pleased with our 2012 operating results, especially in light of some challenging economic headwinds for both tools and diagnostics in many parts of the world. And we anticipate that this challenging economic environment will likely continue into 2013, especially in Europe, as well as potentially in the US with the ongoing uncertainty surrounding sequestration. However, a strong product lineup should help to offset some of these challenges.
We have begun shipping our new benchtop Cell Sorter and will soon launch a next-generation chromatography system used for protein purification in the academic and biopharma market.
On the Diagnostic side of the business, we are looking forward to new products and opportunities in the blood typing, diabetes monitoring and quality controls market. Given this combination of both headwinds and drivers, we are estimating currency neutral sales growth to be in the 3% to 3.5% range for 2013.
With regard to margins, we are hoping to hold the full-year gross margin basically flat around 56%, despite adding $5 million to $10 million of estimated medical device tax and incremental amortization associated with the new cell biology technology.
Looking to the operating margin outlook, we view 2013 as another year of investment and thus are estimating an increase in spend during the year, including an incremental $15 million to $20 million related to our ERP project. The net result of these internal investments and the medical device tax will likely produce an operating margin in the 11% to 11.5% range for the full year. Keep in mind that our 2012 operating margin, excluding the $22 million of accounting reversals I spoke of earlier, was 11.7%.
Also, as I mentioned earlier, we anticipate a full-year effective tax rate of 27% to 29% and CapEx spend of $140 million to $150 million for 2013.
And finally, we would emphasize that this outlook for 2013 does not include our recent acquisition of AbD Serotec. We are currently in the process of analyzing the operations and purchase price valuation. Our best estimate at this time is that the antibody business will add about $20 million to $25 million of incremental sales to the top line in 2013 and be a headwind to operating income in the $7 million to $10 million range, including amortization expense. We will be able to give you a finalized 2013 outlook, including the Serotec business, on our first-quarter earnings call.
And now I'll turn the call over to Norman for a few comments.
Norman Schwartz - CEO, President
Okay. So I guess I would say that while the fourth-quarter sales were encouraging, as Christine says, we do expect the economic malaise to continue in 2013. In the US, it looks like we may bump up against this sequestration and (technical difficulty) continues to be in the doldrums. As a counterbalance to that, we have growing economies in Asia, Latin America, Eastern Europe, again, as a counterbalance.
Christine also mentioned some of the new platforms we have, especially in Life Science, which expand our reach into some key markets and in some cases open up new avenues for us. So while some of these investments we are making in new technologies and systems are having a dampening effect on the bottom line, we obviously feel that they are valuable for the future. And certainly we appreciate your patience as we make these investments to either enter new markets and on the systems side to give us the tools to help us get greater operating leverage as we grow for the future.
So that's about it. With that, I think we'll open it up to questions. Ian?
Operator
(Operator Instructions). Dan Leonard, Leerink Swann.
Dan Leonard - Analyst
Thank you. Just a couple of questions about the topline guidance and one on ERP. So on the topline guidance, is it fair to say that your 3% to 3.5% currency neutral expectation includes the impact of the sequester in the US?
Christine Tsingos - VP, CFO
That's a good question, Dan. I think that if there is some sort of full sequestration, then no, it does not include that, and that would be downsized to that guidance. I think, as Brad has been saying all along, he's seen behavior in the market of people anticipating some sort of slowdown and kind of holding tight to their grant dollars. So, from that respect, we are a little cautious. But if there is a full-on sequestration, then no, that's probably not anticipated in our 3% to 3.5% outlook.
Dan Leonard - Analyst
Okay. And then on a Diagnostics side, how are you thinking about the potential for new screening recommendations in the US? And can you remind -- HIV screening recommendations -- and can you remind us how big your HIV testing business is?
Norman Schwartz - CEO, President
So maybe John will comment a little bit on changes in the screening environment, but as you know, we don't disclose our sales to the level of detail on a product level or even a division basis.
Dan Leonard - Analyst
Okay.
Operator
Paul Knight, CLSA.
Brian Kipp - Analyst
This is actually [Brian Kipp] on behalf of Paul. A question for you. You guys allude to this 3% to 3.5% organic growth in 2013. And touching on that similar economic environment as you saw in 2012, are you going to see -- do you think -- do you expect acceleration in sales like you did or kind of a similar trend as you did in 2012, or do you think it's going to -- basically are you worried about it coming out of the gate in first quarter and accelerating through fourth quarter?
Christine Tsingos - VP, CFO
I think -- so good question. When we build our forecast, we try and do it on a currency neutral basis, and look at what the rates were last year. And setting aside the comments that we just made on sequestration, which could affect the Q1 rate, I think that if currency doesn't change much from where it's been and where it was in the average year, then I think the growth will be fairly ratable with the exception of Q4 of 2013; I'm not sure. We just posted a pretty strong quarter and it could end up being a tough compare for us when we are all sitting here a year from now. But we'll see.
Paul Knight - Analyst
Thank you for that. I guess one follow-up. Did you guys -- you alluded to some strength in the US and some strength in Asia and some softness in Europe. Can you provide any more color on that numbers, any segments that did a little bit stronger, weaker than others?
John Goetz - VP, Clinical Diagnostics Manager
This is John Goetz on the Diagnostic side of the business. We had a good strong quarter, particularly in a couple of product lines, diabetes being kind of the primary one. We had some exceptional shipments in the fourth quarter, particularly into the Asia-Pacific market, and we also finished the year nicely up in the United States. So, a combination of those two things put us in pretty good position.
Brad Crutchfield - VP, Life Science Manager
This is Brad Crutchfield. As far as the Life Science business in the US, certainly the Digital PCR and process cryptography were particular strong and helped kind of offset the slowness of the sort of traditional research business across the academic sector. And again, we continue to see some strength and continue to (technical difficulty) Asia-Pacific.
Paul Knight - Analyst
Okay. Can you guys -- is there any way you could give if it was low single-digit growth in the regions, or mid-single, or is that as deep as you guys can go?
Christine Tsingos - VP, CFO
Historically, we really haven't gotten to the level of detail of talking about growth rate by region or product line.
Paul Knight - Analyst
Okay, well, thank you.
Operator
Jon Wood, Jefferies.
Jon Wood - Analyst
Thanks a lot. Good afternoon. I guess, following up on the last one, so for John, it sounds like it was pretty broad-based in your business. I understand the diabetes call out, but was there any tender related business or was it just actual execution, more of an execution dynamic than an actual a lumpiness dynamic in the fourth quarter? I guess the same question for Brad on the process business. I know that business moves around a lot. So I would be curious to hear if you can kind of call out, hey, that was 1%, 2% nonrecurring benefit, or if it's not possible to do that from an order perspective.
John Goetz - VP, Clinical Diagnostics Manager
On the diagnostic side, we are fulfilling tenders all the time. So there's no special fourth-quarter phenomenon associated with exceptional tender fulfillment. Having said that, driving that sales in the fourth quarter was pretty broad across almost every product line that we have. So there was a lot of good execution around the world I'd have to say.
Brad Crutchfield - VP, Life Science Manager
This is Brad. Concerning the process business, you are correct. It was particularly strong in the fourth quarter, but overall a pretty strong year. As you know, a lot of the this relates to the clinical trials (technical difficulty) FDA approval. So overall, I would say that we raised the bait for this business in 2012 as a result of a number of processes we are in. But again, business will continue to be lumpy quarter-to-quarter, but the growth that we saw was generally (technical difficulty)
Jon Wood - Analyst
Good color. Brad, so can you -- I don't think -- I think Christine kind of alluded to it but can you give the Quantalife number in the fourth quarter and anything you are willing to offer? I know that was a particularly strong number -- kind of how you see that shaking out in 2013.
Christine Tsingos - VP, CFO
So Jon, now that we've kind of rounded our one-year anniversary on Quantalife being part of our results, for the fourth quarter, we consider it organic to our business. So it's not a specific number that we're going to be disclosing.
Jon Wood - Analyst
Okay. So there was no -- I think you gave a number down 1.2% organically for the Life Science business. Is that right, for the year?
Christine Tsingos - VP, CFO
I don't know. I'll look it up.
Jon Wood - Analyst
Okay. Christine, can you talk about just how much that business kind of dragged your OP, at least in '12? You don't have to give a '13 number. I'd like to hear ultimately did that business come in within that initial $20 million burn rate?
Christine Tsingos - VP, CFO
Yes, I think -- in fact, I think we were talking about as much as $25 million between the amortization and the operating results, and that's about where it came in.
Jon Wood - Analyst
True. Anything Brad can offer on Propel? Can you call that -- I would assume that's in your 3% to 3.5% number. Are you all willing to quantify what that contributes in 2013?
Brad Crutchfield - VP, Life Science Manager
I certainly won't be able to quantify it specifically other than to say the product is launched and we are taking orders and making deliveries off the product. So far the (technical difficulty) seems to have hit a really nice (technical difficulty) sorting market.
Jon Wood - Analyst
Good. Last one, so Christine, you talked about the ERP spending being up $15 million to $20 million. That's a P&L number, correct, in 2013?
Christine Tsingos - VP, CFO
It is a P&L number. And what's behind that number are several things. Some -- obviously we need to start depreciating. We plan to go live with the first deployment early in the first half of 2013. And thus we will have to start taking on some depreciation associated with that. There's also a fair amount of related support and other expense associated with the go live that we will be taking on and then maybe a small increment in the project itself, but a lot of it has to do with going live with our first deployment.
Jon Wood - Analyst
Okay. Did you call out the amount of capital in that $140 million to $150 million related to the capitalization?
Christine Tsingos - VP, CFO
We did not.
Jon Wood - Analyst
Can you?
Christine Tsingos - VP, CFO
Are you talking about how much of it relates to ERP?
Jon Wood - Analyst
Yes ma'am.
Christine Tsingos - VP, CFO
It's $35 million to $40 million.
Jon Wood - Analyst
Very good, thanks a lot.
Operator
Jeffrey Matthews, Ram partners.
Jeffrey Matthews - Analyst
Hi everybody. Can you hear me?
First, you called out Latin America, and I don't ever recall you calling that out before. How significant is that as a market for you down the road, do you think?
Brad Crutchfield - VP, Life Science Manager
We have actually called it out before. It is becoming a more significant market for us as it grows. They seemed to be getting -- Latin America seems to be more stable today than it was many years ago, and we've been investing in that market. So, it is becoming a more significant market for us. Still relative to the rest of the world it's small, but it's measurable.
Christine Tsingos - VP, CFO
Yes, I think that's right. It's still single digits in terms of percent of overall sales, but certainly one of our fastest growing markets.
Jeffrey Matthews - Analyst
Okay. And then Norman talked about new platforms in Life Science that open up new avenues for you. Could you talk a little bit about what those avenues are and how important they might get to you down the road?
Norman Schwartz - CEO, President
Actually Brad might be able to talk about this a little better, but I think, especially in this area of cell biology, if you look at the past, we've concentrated on the researchers studying genes and proteins, and this is kind of the third segment, people studying cells. And so the idea of this kind of platform and intro into the cell biology market or the cell assay market is really a new avenue for us. Brad, anything to add?
Brad Crutchfield - VP, Life Science Manager
Yes. I think if we look at the platforms, you can look at cell biology as a front end to our workflow. It's really the way customers are looking at single cell biology. We are sorting their cells before they begin their research. Certainly the QX100, and then followed on into our protein characterization platform, so traditional Western blot platforms are all going to benefit by having content, this biologically relevant content. Last year, we introduced the complete human genome. We have the mouse genome coming very (technical difficulty) this year, and then the acquisition of AbD Serotec is the antibody content to go on the Cell Sorter as well as to go on our Western blot platform. So really for us, it's kind of a vertical integration strategy, not just a platform and some of the reagents but the biologically relevant content. It's kind of our strategy going forward.
Jeffrey Matthews - Analyst
Okay. Is there something about what's going on now that makes this the time to have done it rather than years past, or not?
Brad Crutchfield - VP, Life Science Manager
I think part of it is that a lot of the data around next gen sequencing has opened up a lot of information that ultimately has to be validated by protein expression. The only way to do protein expression of course is in some cases (technical difficulty) looking at very rare events, so you have to do single cell biology, but that certainly (technical difficulty) well up with the Cell Sorter. But then the other side is traditional tools for looking at very slight nuances to protein expression ultimately to validate what is genomic information.
Jeffrey Matthews - Analyst
I see. Okay, great. And then finally on the ERP, implementation, what inning are you in on the implementation, and what surprises, if any, are you experiencing? And has there been any change in the timetable for when it begins to switch from being a cost item strictly to being a benefit to working capital and margins?
Christine Tsingos - VP, CFO
Okay. I think we are still somewhat early in the game here, early innings in terms of the overall project. Remember when we started on this journey, we talked about it being a four- to five-year project for us, wanting to take a fair amount of time upfront to work on a good global design that we could truly replicate around the world and try and get to a single platform, a single system. And then also talked about that we want to be pretty deliberate in how we roll this out, not -- none of us really having the stomach for a big bang approach, and moving into our first deployment which is a small part of the US as a proof of concept, if you will, and try to take it from there. So, that's where we are now. A lot of the design is behind us and we are getting close to going live with that first deployment.
In terms of what we know now that maybe we didn't know before, we kind of knew this was going to be hard, and it truly is hard. At the same time, we suspect there are fair amount of benefits, and I think we're going to find that there are. As we move forward through this, we need to start making some decisions about what is the most effective way to get to the finish line vis-a-vis how we move geographically around the world in terms of further implementation, either on a geographic business or a line of business aspect, and we are looking at that now. Clearly, for us to take this system abroad is a very complex task that will take a fair amount of planning, so that actually may push the time line out a little bit for the international locations. But at the same time, I think there's plenty that we can continue to achieve here in the US.
Jeffrey Matthews - Analyst
Okay, great. Thanks. That make sense. Appreciate it.
Operator
Matthew Goetzinger, Fiduciary.
Matthew Goetzinger - Analyst
Thanks for taking the question. Just a broader question. We've been around the shareholders for a little bit of time, and it always seems like there's some interesting slate of business opportunities, whether it is the Bio-Plex or the IH 1000 or otherwise. And early earnings just happened to (technical difficulty) for a couple of years here. And so I guess my question is what's the level of management commitment to really drive earnings back to the $6 to $7 range?
Brad Crutchfield - VP, Life Science Manager
I think we're pretty committed to doing that. I mean we are not making these investments just for fun. We want the return on those investments, and we have taken our margins down in order to do these things, again, because we feel that they will give us the right kind of leverage for the future. And so I think we are pretty well committed to where that's kind of our internal goal is to get back to the mid to high teens in terms of operating margin.
Christine Tsingos - VP, CFO
Yes, and I would agree with that. I think sometimes it's hard for us as it sounds like it may be for you from time to time as we look at this, and the short-term impact on our P&L, especially when we made such progress in growing our margins from the single digits up to that high 14%. But in the end, we keep coming back to if we don't make this investment, we are not going to have the strong foundation that we need to be scalable moving forward, but more importantly the technology that will help us take some of the redundancy out of our business that we have on a global basis. So each time we look at what this is, we become very committed to continuing down this path so that we can build that foundation, and therefore fulfill our commitment to actually expand our earnings power in the future.
Matthew Goetzinger - Analyst
Yes, I think that's helpful and intuitive. I think the time line or a commitment to a time line seems to be kind of slipping, and then there always seems to be something technologically interesting like a Serotec or otherwise that comes along that for whatever reason sounds like it is operating at a meaningful loss position from the get-go. And it just seems like that does back here another year or two. So I guess I'm just struggling with the patience factor in the time line here.
Christine Tsingos - VP, CFO
Fair enough.
Operator
Jeffrey Warshauer, Sidoti & Co.
Jeffrey Warshauer - Analyst
Good afternoon. Thanks for the questions. So did I hear you accurately before? Did you mention beyond the 3% to 3.5% sales growth, you threw out a number $20 million to $25 million in incremental sales from acquisition?
Christine Tsingos - VP, CFO
That's correct.
Jeffrey Warshauer - Analyst
And how much of that do you think you could see in the first quarter due to the closing of the recent acquisition in the first quarter?
Christine Tsingos - VP, CFO
That's a good question. Probably -- if history is any judge, as we've done other -- bringing other acquisitions into the fold, my guess would be, at this point, that it would be more back-end loaded because history shows us in the first few months of bringing something in there's always a big focus on integration and getting to know the business, and we tend to see growth in the latter quarters. So, I'm not sure that the increment in Q1 is substantial. But again, we're just trying to get our arms around that business, having recently closed it.
Jeffrey Warshauer - Analyst
Okay. Thank you. And relative to going live in the ERP and your expectations in the US, maybe you could give a better time line, if you could, on how you think you will proceed throughout this year and when you think you could go live in Europe.
Christine Tsingos - VP, CFO
So right now, we are hoping that, sometime in the second quarter, this first deployment in the US -- and again it's one of our smaller divisions based in the US so it's not -- I wouldn't characterize it as all the US -- hoping to go live in the second quarter. And then the remainder of this year, the balance of this year, will be spent planning and finalizing design and actually developing our second deployment.
I think, as far as timing for Europe, given the complexity of Europe and the number of legal entities and manufacturing sites, distribution sites, etc., that we have, we are probably still -- oh my gosh -- 18 months to 24 months away from really getting into Europe and starting to bring those various entities into the fold.
Jeffrey Warshauer - Analyst
Do you think that's from going live in Europe, 18 to 24 months?
Christine Tsingos - VP, CFO
I think -- I'm not sure from what direction you're asking your question. If your question is when do we start going live with all of these multiple operations that we have, it's not one big bang in Europe either. So could we start to go live in a 24-month window with smaller operations? Sure. But if your question is when do you really have Europe into the fold, and therefore when do you start see the benefits because we've spoken in the past how Europe holds the key to the largest benefits of this project --
Jeffrey Warshauer - Analyst
Right.
Christine Tsingos - VP, CFO
If that's where your question is coming from, then it's at least 24 months away and most likely longer than that before we have all of Europe in the fold and producing a benefit.
Jeffrey Warshauer - Analyst
Okay. That's helpful. Thanks. And lastly, regarding your patent investment in Sartorius, is there any way to potentially generate additional value from that investment through collaboration or unlocking value through monetization?
Norman Schwartz - CEO, President
There are always those options, yes.
Jeffrey Warshauer - Analyst
Can you provide any insight into what you might be looking at?
Norman Schwartz - CEO, President
No.
Jeffrey Warshauer - Analyst
Okay. That will be it. Thanks.
Operator
Jon Wood, Jeffries.
Jon Wood - Analyst
Hello. So, you've got some extremely high coupon debt coming that you can kind of call in September. Can we assume that you guys do that, so I think it's September 15, should we assume you can call that and maybe put it out into some longer-term, more favorably financed paper?
Christine Tsingos - VP, CFO
Yes, so a good question. I think we are looking forward to September as much as you are so that we can refinance or take out. We will make that decision as we get closer to it, that 8% debt. And I should say that that's not factored into the discussion we had today on our outlook.
Jon Wood - Analyst
Okay, great. Christine, we haven't talked about this I don't think publicly, but you guys have obviously a lot of cash on the balance sheet. I would assume a fair amount of that is overseas. Can you talk about how much you can access on your balance sheet without having to go through some tax consequences? Just so we understand about what is immediately deployable and what is perhaps earmarked for more of an M&A or longer-term tax planning situation?
Christine Tsingos - VP, CFO
Okay. Sure. So as I mentioned in the prepared remarks, it's about $921 million on the balance sheet. The vast majority is actually here in the US. I think maybe up to $200 million is sitting outside the United States, of the $921 million. And of course we have operations all over the US and a lot of those require continued investments. And we have been making some acquisitions outside the United States, for example the most recent AbD Serotec one where we can use some of that cash.
But in terms of tax planning, we do consider it a permanent reinvestment and are continuing to invest and expand internationally not just via acquisitions but through organic investment and manufacturing, etc. But the majority of the cash does sit here and gives us the flexibility to invest internally and externally in acquisitions and things like that. Does that answer your question, or are you heading somewhere else with this?
Jon Wood - Analyst
No, that's great. Thanks a lot.
Operator
We have no further questions in the queue.
Christine Tsingos - VP, CFO
Great. Thank you everyone for taking the time to join us today, and hopefully we will be seeing you soon. Bye-bye.
Operator
Thank you ladies and gentlemen. That concludes your conference call. You may now disconnect. Thank you very much for joining us today. Do enjoy the rest of your day.